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What is the central theme of molecular genetics? Now let's look at the entire process of taking DNA and creating Proteins from that code: Say we have the following nucleotide chain in DNA: T-A-C-T-A-G-C-G-G-A-T-A-G-C-A-T-C-C-C-G-G-G-A-T-A-T-T DNA What happens during the event called transcription?

What is the central theme of molecular genetics? Now let's look at the entire process of taking DNA and creating Proteins from that code: Say we have the following nucleotide chain in DNA: T-A-C-T-A-G-C-G-G-A-T-A-G-C-A-T-C-C-C-G-G-G-A-T-A-T-T DNA What happens during the event called transcription?

Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 10QP: If the coding region of a gene (the exons) contains 2,100 base pairs of DNA, would a missense...
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In the early 1960's scientists knew the structure of DNA, however they didn't know how it coded for the expression of proteins. To find out, American Biochemist, Marshall Nirenberg did an experiment and figured out the first codon! To begin he made a solution of Uracil (U), and linked the nucleotides together to form a synthetic RNA molecule which read-UUUUUUU... etc. Therefore, no matter where the message started or stopped, the codon triplets always read UUU, UUU, UUU. Next, he added the poly-U chain to a solution of ribosomes and other ingredients needed for polypeptide synthesis. The result was a polypeptide containing the amino acid phenylalanine. Thus, Niernberg learned that the RNA codon UUU specifies the amino acid phenylalanine. What is the central theme of molecular genetics? Now let's look at the entire process of taking DNA and creating Proteins from that code: Say we have the following nucleotide chain in DNA: T-A-C-T-A-G-C-G-G-A-T-A-G-C-A-T-C-C-C-G-G-G-A-T-A-T-T DNA What happens during the event called transcription? Which DNA bases are complementary to the RNA bases? Now, what would that RNA code be to the DNA (in the box below)? T-A-C-T-A-G-C-G-G-A-T-A-G-C-A-T-C-C-C-G-G-G-A-T-A-T-T DNA RNA Based on our RNA code (the string of nucleotides) - we can create triplet codons that will code for amino acids. Write the list (from above) of triplet codons out, separating each codon by a hyphen (ex. ABC-DEF-GHI...etc.). Based on the sequence of triplet codons written above, write out the associated amino acid sequence as determined by the RNA codons (separate the amino acids with a hyphen). The codon table with amino acid sequence is in figure 10.9 of your textbook - writing the three letter amino acid abbreviation is fine. Notice/indicate the "Start" and "Stop" codons.
Transcribed Image Text:In the early 1960's scientists knew the structure of DNA, however they didn't know how it coded for the expression of proteins. To find out, American Biochemist, Marshall Nirenberg did an experiment and figured out the first codon! To begin he made a solution of Uracil (U), and linked the nucleotides together to form a synthetic RNA molecule which read-UUUUUUU... etc. Therefore, no matter where the message started or stopped, the codon triplets always read UUU, UUU, UUU. Next, he added the poly-U chain to a solution of ribosomes and other ingredients needed for polypeptide synthesis. The result was a polypeptide containing the amino acid phenylalanine. Thus, Niernberg learned that the RNA codon UUU specifies the amino acid phenylalanine. What is the central theme of molecular genetics? Now let's look at the entire process of taking DNA and creating Proteins from that code: Say we have the following nucleotide chain in DNA: T-A-C-T-A-G-C-G-G-A-T-A-G-C-A-T-C-C-C-G-G-G-A-T-A-T-T DNA What happens during the event called transcription? Which DNA bases are complementary to the RNA bases? Now, what would that RNA code be to the DNA (in the box below)? T-A-C-T-A-G-C-G-G-A-T-A-G-C-A-T-C-C-C-G-G-G-A-T-A-T-T DNA RNA Based on our RNA code (the string of nucleotides) - we can create triplet codons that will code for amino acids. Write the list (from above) of triplet codons out, separating each codon by a hyphen (ex. ABC-DEF-GHI...etc.). Based on the sequence of triplet codons written above, write out the associated amino acid sequence as determined by the RNA codons (separate the amino acids with a hyphen). The codon table with amino acid sequence is in figure 10.9 of your textbook - writing the three letter amino acid abbreviation is fine. Notice/indicate the "Start" and "Stop" codons.
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