1A. Explain why solvents such as anhydrous diethyl ether or anhydrous tetrahydrofuran (THF) are not reactive with Grignard reagents.

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter8: Haloalkanes, Halogenation, And Radical Reactions
Section: Chapter Questions
Problem 8.28P
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answer must be typed/digitally illustrated if applicable (cannot be hand drawn - it will be marked as incorrect if it is hand drawn)

1A. Explain why solvents such as anhydrous diethyl ether or anhydrous tetrahydrofuran (THF) are not
reactive with Grignard reagents.
1B. Draw the first step of the reaction mechanism when the Grignard reagent attacks benzophenone
before the alkoxide is protonated to form the alcohol. In the mechanism, identify the partially positive
and partially negative atoms in the reactants. Explain why these atoms have a partial charge.
1C. Write the mechanism for the reaction of phenyl magnesium bromide with 1) water and 2) acetone.
Transcribed Image Text:1A. Explain why solvents such as anhydrous diethyl ether or anhydrous tetrahydrofuran (THF) are not reactive with Grignard reagents. 1B. Draw the first step of the reaction mechanism when the Grignard reagent attacks benzophenone before the alkoxide is protonated to form the alcohol. In the mechanism, identify the partially positive and partially negative atoms in the reactants. Explain why these atoms have a partial charge. 1C. Write the mechanism for the reaction of phenyl magnesium bromide with 1) water and 2) acetone.
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