2. As part of the natural product synthesis for a potential new drug, an aliphatic Fridel-Crafts acylation is employed from the following acid chloride, giving two products, 1 and 2. Propose a plausible mechanism for the formation of products 1 and 2. H CI AICI 3 H CI -. 1 2

2. As part of the natural product synthesis for a potential new drug, an aliphatic Fridel-Crafts acylation is employed from the following acid chloride, giving two products, 1 and 2. Propose a plausible mechanism for the formation of products 1 and 2. H CI AICI 3 H CI -. 1 2

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter19: Enolate Anions And Enamines

Section19.8: Conjugate Addition To A,b-unsaturated Carbonyl Compounds

Problem 19.13P

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2. As part of the natural product synthesis for a potential new drug, an aliphatic Fridel-Crafts acylation
is employed from the following acid chloride, giving two products, 1 and 2. Propose a plausible
mechanism for the formation of products 1 and 2.
H
AICI 3
$-4.
H
1
CI
2

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