2. Describe the effect of the mutation that created the Hbs allelelon the amino acid sequence of the beta globin polypeptide chain: effect of mutation on codon, which amino acid was changed (#amino acids from beginning of chain), what was the amino acid change (from which amino acid to which amino acid?) Lmurtion in tho bnto-alohinchain affects the bemoalobin.component. The

2. Describe the effect of the mutation that created the Hbs allelelon the amino acid sequence of the beta globin polypeptide chain: effect of mutation on codon, which amino acid was changed (#amino acids from beginning of chain), what was the amino acid change (from which amino acid to which amino acid?) Lmurtion in tho bnto-alohinchain affects the bemoalobin.component. The

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter18: Evolution And The Origin Of Species

Section: Chapter Questions

Problem 6RQ: Which description is an example of a phenotype? A certain duck has a blue beak A mutation occurred...

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Discuss Concepts Many human diseases are caused by recessive alleles that are not expressed in heterozygotes. Some people think that eugenicsthe selective breeding of humans to eliminate undesirable genetic traitsprovides a way for us to rid our populations of such harmful alleles. Explain why eugenics cannot eliminate such genetic traits from human populations.
Which description is an example of a phenotype? A certain duck has a blue beak A mutation occurred to a flower Most cheetahs live solitary lives both a and c
4) The government of Iceland has built a database which contains genetic informaiton about individuals using SNP analysis and other methods, which can be used to help diagnose pre-disposition to genetic diseases and other conditions. What are some ethical issues that are raised by compiling such a database?
6) If you had the ability to do gene editing with ONE gene for the betterment of human kind, which one would you choose, and why? Assume you could either change an abnormal allele associated with a disease, such as the cystin gene associated with Cystic Fibrosis to its normal wild type, or add a pre-existing human allele to a genome
1. The first genetic test developed for this disease took advantage of a large family of over 2,000 individuals who lived along Lake Maracaibo in Venezuela. These family members, some with and some without Huntington’s disease, could all trace their ancestry to a single female who settled in the region a number of generations ago.Genomic DNA from family members with and without Huntington’s disease was cut with a set of enzymes that make reproducible cuts at known DNA sequences. These DNA fragments were run on a DNA gel to see which fragments correlated with the presence of Huntington’s disease. a) How might the large number (over 2,000) of family members who have a common ancestor who suffered from Huntington’s disease make it easy to narrow down the gene location of the Huntington’s locus (compared to doing the same experiment with a small family descended from a Huntington’s sufferer)?
1. What advantages do anonymous DNA markers afford for genetic mapping as opposed to traditional allelic markers associated with visible phenotypes? What are the disadvantages of anonymous DNA markers for mapping? 2. Would you be more likely to find SNPs in the protein-coding or in the noncoding DNA of the human genome?
1. Below is the base sequence of protein for normal hemoglobin and the base sequence for the sickle cell hemoglobin:Normal: GGG CTT CTT TTTSickle: GGG CAT CTT TTTa. Transcribe and translate the normal and sickle cell DNA. b. Identify this as a point or frameshift mutation. Explain. c. If the base sequence read GGG CTT CTT AAA instead, would this result in sickle cell hemoglobin? Explain.
6. what is The theory that genetic information is transmitted from one generation to the next as discrete units?
1. Briefly explain how differences in TWO specific traits make evolution in whales slow and evolution in influenza fast. 2. Is reassortment between just one avian strain and one swine strain of influenza likely to pose a risk to humans? Why or why not?
7. Why recombinant DNA is very useful in improving our health conditions?A. Human insulin can be reproduced by bacteria?B. Vaccine can be reproduced by fungi or bacteriaC. Human growth hormone can be obtained from E. ColiD. All of the above 8. Which of the following is/are example of genetic engineering?A. A farmer choose a breed of cow for greater milk production.B. The use of bacteria in order to produce human insulinC. The insertion of clone genes to plant cellsD. Cross pollination of squash flowers. 9. Bacterial cells as host organisms may expose the gene to make protein products such as insulin and growth hormone . Which of the following processes are involved?A. replication and transcription. B. Transcription and replication C. Transcription and transformation. D. Replication and transformation
2. Null mutations are valuable genetic resources becausethey allow a researcher to determine what happens to anorganism in the complete absence of a particular protein. However, it is often not a trivial matter to determinewhether a mutation represents the null state of the gene.a. Geneticists sometimes use the following test forthe nullness of an allele in a diploid organism: If theabnormal phenotype seen in a homozygote for theallele is identical to that seen in a heterozygote(where one chromosome carries the allele in question and the homologous chromosome is known tobe completely deleted for the gene) then the alleleis null. What is the underlying rationale for thistest? What limitations might there be in interpreting such a result?
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