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- Explain the objective for preparation of p-Iodonitrobenzene.What is the major benefit of refluxing? Why might reflux conditions be required for this reaction (Friedel-Crafts Alkylation)?Briefly explain why the Suzuki reaction can take place in aqueous solution whereas a Grignardreaction requires anhydrous conditions.
- Although derivatization of a reaction should be avoided as much as possible according to the principles of green chemistry, the protective groups needed in organic synthesis mainly regulate the chemoselectivity of the reaction. Mention only 3 requirements for a good protective group !To illustrate rearrangement in the Friedel-Crafts alkylation reaction draw the structure of the two products obtained in the reaction between benzene and 2-bromopropane in the presence of AlCl3. Briefly explain the rationale for the selectivity.Suggest and explain two synthetic methods for the conversion of compound 6 to compound 4. Include side reactions
- i need help writing all of the detailed methods: in Preparation of Cyclohexanone by Hypochlorite Oxidationprepare a flow sheet for the preparation of benzoic acid from a) bromobenzene and magnesium and b) phenylmagnesium bromide and carbon dioxide. using your knowledge of the physical properties of the solvents, reactants, and products, show how the products can be purified, indicate which layer should contain the product in the liquid/liquid extraction steps.write the reaction of the action of methyl-2, bromo-2-propane with hot KOH solution. a) Name the formed product b) Explain why the reaction takes place according to the SNI mechanism