Plz asap 2. Match the correct molecules with the checkpoints below.a. Molecules important for regulating checkpoints (in random order): Anaphase-Promoting Complex (APC), Retinoblastoma (Rb), Mitosis-Promoting Factor (MPF)b. and indicate whether the molecule/complex is an oncogene or a tumor suppressor inthe last column.Checkpoint Table.1. Checkpoint name:G1/S checkpointG2/M checkpointSpindle Assembly Checkpoint (SAC)2. Molecule(s) needed 3. Cancer connection

There are various phases in the cell cycle and various checkpoints present so that if the DNA is…

2. Match the correct molecules with the checkpoints below. a. Molecules important for regulating checkpoints (in random order): Anaphase- Promoting Complex (APC), Retinoblastoma (Rb), Mitosis-Promoting Factor (MPF) and indicate whether the molecule/complex is an oncogene or a tumor suppressor in the last column. b. Checkpoint Table. 1. Checkpoint name: G1/S checkpoint G2/M checkpoint Spindle Assembly Checkpoint (SAC) 2. Molecule(s) needed 3. Cancer connection

2. Match the correct molecules with the checkpoints below. a. Molecules important for regulating checkpoints (in random order): Anaphase- Promoting Complex (APC), Retinoblastoma (Rb), Mitosis-Promoting Factor (MPF) and indicate whether the molecule/complex is an oncogene or a tumor suppressor in the last column. b. Checkpoint Table. 1. Checkpoint name: G1/S checkpoint G2/M checkpoint Spindle Assembly Checkpoint (SAC) 2. Molecule(s) needed 3. Cancer connection

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter17: Biotechnology And Genomics

Section: Chapter Questions

Problem 3VCQ: Figure 17.15 In 2011, the United States Preventative Services Task Force recommended against using...

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1. Put the steps of cdk-cyclin regulation in order. a) Cyclin protein is made b) the cell passes the checkpoint c) the cdk and checkpoint proteins are inactive d) cyclin protein is degraded e) cyclin protein binds to cdk protein and activates it f) cdk phosphorylates a checkpoint protein
2. Characterize the differences between tumor cells andnormal cells in terms of the following properties. Incancer cells, how might each of these propertiescontribute to tumor progression?a. contact inhibitionb. autocrine stimulationc. apoptosisd. telomerase expressione. senescence due to telomere shortening
1. a. What are the three categories of genes mutated in cancer cells? What is the effect of mutation of each? b. What is the function of checkpoint controls in the cell cycle? What is checked at G1, S, G2 and M phase before the cell can progress to the next phase?
Which of the following is typical of cancer cells? A. The parent cell of the tumor contains a single mutation in a single checkpoint gene. B. Malignant cells migrate. C. Cancer cells lose the ability to divide. D. Products of oncogenes inhibit mitosis E. Benign tumors invade normal tissue.
Figure 17.15 In 2011, the United States Preventative Services Task Force recommended against using the PSA test to screen healthy men for prostate cancer. Their recommendation is based on evidence that screening does not reduce the risk of death from prostate cancer. Prostate cancer often develops very slowly and does not cause problems, while the cancer treatment can have severe side effects. The PCA3 test is considered to be more accurate, but screening may still result in men who would not have been harmed by the cancer itself suffering side effects from treatment. What do you think? Should all healthy men be screened for prostate cancer using the PCA3 or PSA test? Should people in general be screened to find out if they have a genetic risk for cancer or other diseases?
Which of the following is not true of somatic cell gene therapy? a. White blood cells can be used. b. Somatic cells are cultured, and the desired DNA is introduced into them. c. Cells with the introduced DNA are returned to the body. d. The technique is still very experimental. e. The inserted genes are passed to the offspring.
Which of the following statements about cell cycle regulators is incorrect? a. The concentrations of cyclins change throughout the cell cycle. b. Cyclins are present in all stages of the cell cycle except S. c. Cyclin-Cdk complexes phosphorylate target proteins. d. Cdks combine with cyclin to move the cycle into mitosis. e. During anaphase of mitosis, cyclin is degraded, allowing mitosis to end.
1.The cells of cancerous tumors undergo changes that cause them to bear little to no resemblance to their original cell type. Predict how this will affect the ability of thise cells to perform thier function. A. Increased growth in the thickness in the alveolar tissue of lungs can allow fir more oxygen and can be detrimental if too much gas exchange occurs. B. Increase in abnormal growth in compact bone tissue can cause bones to become stronger. C. Tumor in the bladder can lead to the disproportionate growth of the epithelial tissue that allows the bladder to stretch; therefore, it will create a constant urgency to urinate. D. All choices are correct (I think it's between A and C but not sure which one)
14) this is the serine protein kinase that when activated in a MPF complex that results in triggering the change in structure seen during mitosis. a) cyclin A/B b) Wee 1 c) TOR( target of rapamycin d)cdk1 e) none of these
1. One of the following sentences is NOT correct A. P53 is an example of tumour suppressor gene B. Wright's stain is sued to visualize a peripheral blood smear C. leukotrienes are derived from arachidonic acid by cyclooxygenase D. effective bacteriocidal enzymes are contained in lysosome of the neutrophils E. H&E stain is the most commonly used tissue stain for routine histological examination F. proteoglycans are located in the ECM but not in the ground substance of connective tissue 2. Which of the following sentences is NOI correct? A Microvilli increase the surface area of the epithelial cells B. Desmosomes are an effective barrier to the diffusion of substances across an epithelium C. Epithelial tissues are classified by the shape of the epithelial cells in the basal layer D. Release of lipid droplets from cells is a type of merocrine secretion E. Epithelial tissues are classified by the number of cell layers F. None of the above G. Both A and E H B. C and D 3. Which of the…
With regard to cancer cells, which of the following statementsare true?A. Cancer cells are clonal, which means they are derived from asingle mutant cell.B. To become cancerous, cells usually accumulate multiplegenetic changes that eventually result in uncontrolledgrowth.C. Most cancers are caused by oncogenic viruses.D. Cancer cells have lost the ability to properly regulate celldivision.
a. Why are cell cycle checkpoints important? b. What happens to a cell that fails to meet the requirements of a checkpoint and is not able make the necessary improvements or repairs?