Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Textbook Question
Chapter 10, Problem 8TYK
Which of the following statements about cell cycle regulators is incorrect?
a. The concentrations of cyclins change throughout the cell cycle.
b. Cyclins are present in all stages of the cell cycle except S.
c. Cyclin-Cdk complexes phosphorylate target proteins.
d. Cdks combine with cyclin to move the cycle into mitosis.
e. During anaphase of mitosis, cyclin is degraded, allowing mitosis to end.
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Researchers studying cell cycle regulation in budding yeast have observed that a mutation in the CDC15 gene causes cell cycle arrest in telophase when the yeast cells are incubated at an elevated temperature. Which of the following statements best predicts the effect of the cell cycle arrest on proliferating yeast cells?
A. Restate the question and record the right answer.
B. Why is this the correct answer?
Which of the following statements about the cell cycle is TRUE?
a. The protein APC blocks cells from entering anaphase
b. CDKs are degraded after each cell cycle phase by the addition of a ubiquitin chain to the proteins
c. A kinase is a protein that adds a ubiquitin chain to other proteins Cyclin activity is necessary, but not always sufficient, for CDK activation
d. Cyclin proteins must be degraded before Cdk proteins can be activated
Maturation promoting factor, MPF, is a cyclin-CDK complex that catalyzes the phosphorylation of other proteins to start mitosis. The activity level of MPF is dependent on the relative concentrations of the cyclin and CDK components of MPF (Figure 1).
Based on Figure 1, which of the following describes the role of cyclin in the regulation of the cell cycle?
a.During S phase, the cyclin level remains the same because DNA replication is occurring.
b.During G2 phase, the cyclin level remains low, causing MPF activity to decrease, which leads cells to initiate mitosis.
c.During G1 phase, the cyclin level decreases to signal the start of the resting phase of the cell cycle.
d.During M phase, the cyclin level peaks, resulting in an increased binding frequency with CDK.
Chapter 10 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 10.1 - What are the three interrelated systems that...Ch. 10.1 - Prob. 2SBCh. 10.1 - Prob. 3SBCh. 10.1 - Prob. 4SBCh. 10.2 - Compare the chromosome content of daughter cells...Ch. 10.2 - Prob. 2SBCh. 10.2 - Prob. 3SBCh. 10.3 - How does spindle formation differ in animals and...Ch. 10.3 - Prob. 2SBCh. 10.4 - Prob. 1SB
Ch. 10.4 - Prob. 2SBCh. 10.4 - What is an oncogene? How might an oncogene affect...Ch. 10.4 - Prob. 4SBCh. 10.5 - Prob. 1SBCh. 10.5 - Prob. 2SBCh. 10 - During the cell cycle, the DNA mass of a cell:...Ch. 10 - A tumor suppressor protein, p21, inhibits Cdk1....Ch. 10 - A major difference between hereditary information...Ch. 10 - The major microtubule organizing center of the...Ch. 10 - Prob. 5TYKCh. 10 - Which of the following statements about mitosis is...Ch. 10 - Prob. 7TYKCh. 10 - Which of the following statements about cell cycle...Ch. 10 - Which of the following is not a characteristic of...Ch. 10 - Which of the following does not accurately...Ch. 10 - In bacteria: a. several chromosomes undergo...Ch. 10 - Prob. 12TYKCh. 10 - Discuss Concepts A cell has 38 chromosomes. After...Ch. 10 - Prob. 14TYKCh. 10 - Prob. 15TYKCh. 10 - Apply Evolutionary Thinking The genes and proteins...Ch. 10 - Biologists have long been interested in the...Ch. 10 - Prob. 2ITD
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- Which of the following statements is a lie?Select one: a. If damaged DNA is detected during the cell cycle, negative regulation is responsible in stopping the cell cycle. b. There are four cyclin proteins involved in the positive regulation of the cell cycle and they have fluctuating levels. c. To activate cyclin-dependent kinases (Cdks), they must bind to another kinase.arrow_forwardIn the mitosis experiment, in what stage were most of the onion root tip cells in? Based on what you know about cell cycle division, what does this imply about the life span of a cell? Were there any stages of the cell cycle that you did not observe? How can you explain this using evidence from the cell cycle?arrow_forwardA cell inherits a mutation in a gene that results in a transcription factor, called NF-kB, constantly being in its active conformation. When active, NF-kB stimulates the expression of cyclins that promote progression of the cell cycle, regardless of other conditions. As a result of this mutation, how would this cell's phenotype be affected by this mutation? A) This cell would have a cancer phenotype B) This cell would grow larger in size, but would never divide C) This cell would likely undergo apoptosis D) This cell would not duplicate its chromosomes .arrow_forward
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