2. Predict the major product of Friedel-Crafts alkylation reaction using the following alkyl chlorides. Write the mechanism for each of the reaction. a) CH;CH CH Cl b) CH:(CH3) CCH CI c) (CH3):CHCH CI

2. Predict the major product of Friedel-Crafts alkylation reaction using the following alkyl chlorides. Write the mechanism for each of the reaction. a) CH;CH CH Cl b) CH:(CH3) CCH CI c) (CH3):CHCH CI

Pushing Electrons

4th Edition

ISBN:9781133951889

Author:Weeks, Daniel P.

Publisher:Weeks, Daniel P.

Chapter6: Valence Electrons (redux)

Section: Chapter Questions

Problem 6EQ

See similar textbooks

Related questions

Q: What change would you expect on the rate of the Sy2 reaction of 1-lodo-2methylbutane with cyanide…

A: The rate of the SN2 reaction of 1-iodo-2-methylbutane with cyanide ion remains unchanged if the…

Q: 2. Give the expected major product of each of the following reaction (sequence, CHO CH3 КОн H*…

A: The detailed solution of the given question is done on the white sheets of paper attached below.…

Q: The two Grignard reactions and the reduction reaction below are all believed to have similar…

A: Reaction involving organic compounds are called organic reactions. Organic reactions are of…

Q: For the reaction below, provide a mechanism for the formation of intermediate A and product B. Show…

A: Reaction 1 : 6 pi electrocyclization and dis rotation is favored under thermal conditions. Reaction…

Q: Explain how and why rearrangements occur during Friedel-Crafts alkylation reactions forming more…

A: Concept - In Friedel-Crafts alkylation reaction is an electrophilic aromatic substitution reaction…

Q: Conc. H2SO4 Но Br HBr a.

A: In a question carbocation is highly stable due to backbonding so Be add on that particular carbon…

Q: 2. What is the major product of the following Friedel-Crafts alkylation? CH3 + CH;CHCH,CI AIC13…

Q: OCH3 AICI3 + CH3¬Ĉ-O-Ĉ-CH3 CH3O- -CH3 + CH3¬Ĉ-OH CH;Az

Q: 1. Explain the following reactions. a. Reactions of 2-butanone and di-t-butyl ketone with CN' are as…

A: Hydrogen cyanide (HCN) undergoes nucleophilic addition reaction with carbonyl compound.In these…

Q: 1) How would you synthesize the compound shown below by using a 2 steps reaction scheme with one of…

Q: The compound shown below can be synthesised by the reaction of alkyl halide and an alkoxide in the…

A: For SN2 reaction alkyl halide should be one degree and alkoxy should be 3 degree for high reactivity…

Q: 6. Give the expected product of the following Michael addition. base

Q: 十 H- Br

A: electron rich species are called nucleophile electron deficient species called electrophile the…

Q: What type of sigmatropic rearrangement is illustrated in each reaction?

A: (a) The pi bond is rearranged and the σ bond is broken in this sigmatropic rearrangement. This…

Q: b) Explain in detail what characteristics of the alkyl halide influence whether a mechanism will be…

A: b) Alkyl Halide reactivity in SN1 mechanism: The order of alkyl halides towards SN1 mechanism…

Q: 2. The reaction of 2-bromo-2-methylbutane with sodium ethoxide at 50 °C leads to the formation of…

Q: 3. A. Provide the major organic product of the reaction below and a detailed, stepwise mechanism…

A: The mechanism for the reaction between given molecule and methanol in the presence of heat is shown…

Q: 8. A Without changing reagent concentrations or amounts, what change could one make to the reaction…

Q: Explain why the reactions below are unlikely to occur as written! a. The SN2 reaction of…

A: Haloalkanes are the compounds that contain a bond between sp3 hybridized carbon and halogen atom.…

Q: 1.A. Complete the following reaction and provide a detailed, step-by-step mechanism for the process.…

Q: Consider the following retrosynchetic analysis for 2-methylhexane: Retrosynthetic Analysis CH,…

A: Detail forward synthesis of every feasible reactions are given below

Q: 2. A limitation of the Friedel-Crafts alkylation reaction is that the presence of…

Q: Consider the E1 reaction of 3-bromo-2-cyclohexyl-butane. How many elimination products are…

Q: 2) Write a detailed mechanism for the following reaction: H2S04 CH;CH;C=CH + H,O CH;CH¿CCH3

Q: OH H C-OH H CH₂ НО

A: Here we are required to predict the mechanism for the reaction.

Q: 1. Draw the MAJOR organic product obtained in the following reactions. Be sure to include…

A: We have to draw product for the following given reactions as follows in step 2:

Q: Reaction 1: Reaction 2: CI CI AICI3 AICI3

A: Friedel craft reaction- Benzene is a nucleophile and addition of electrophile does not takes place…

Q: 2) When 3,3 -dimethylcyclopentene is treated under the two sets of conditions shown below, the main…

A: Organic reaction mechanisms.

Q: 6. Provide the full mechanism for the Friedel-Crafts Acylation reaction in the first step of the…

Q: 9) This molecule CANNOT participate as a reactant in a Friedel-Crafts reaction B) nitrobenzene A)…

A: Friedal crafts reaction is the addition of acetyl CH3CO group or alkyl CH3 group to the compound.…

Q: 2) Write a detailed mechanism for the following reaction: H2SO4 CH;CH,C=CH + H2O CH;CH,CCH3

A: Hydration reaction of Alkyne takes place in acidic medium as follows:

Q: 9.11. When compound 11-A is dissolved in FS0,H at –78°C, the NMR spectrum shows that a carbocation…

A: FSO3H has the ability to protonate a compound.

Q: Q6) (use a Newman or Saw Horse projection) the stereochemical requirements for the E2 elimination…

Q: 5. Optically pure 2-octyl sulfonate was treated with varying mixtures of water and dioxane, and the…

A: SN2 reaction proceeds through inversion in configuration Dioxane acts as a nucleophile. It reacts…

Q: 2. Given the following sequence of reactions, draw the structure of products A and B and write a…

A: The primary amine reacts with the ester to form an amide. This reaction goes via a tetrahedral…

Q: Choose the best set of conditions for a Friedel-Crafts acylation of aromatic compounds. A)…

A: Friedel-Crafts Reaction

Q: 4. Provide the major organic product (elimination rxn): NAOCH. CH;OH Br a. CH3 nCH3 NaOH Br b. КОН,…

A: Since, you have asked multiple question, we will solve the first question for you. If you want any…

Q: 7. Provide the full mechanism for the Friedel-Crafts Alkylation reaction in the third step of the…

Q: 6. Consider the following reaction scheme: 1) l2, NAOH, H,0 2 OH + ICH3 2 2) H30* Draw a detailed…

Q: 3-Bromocyclohexene is a secondary halide, and benzyl bromide is a primary halide. Both halides…

A: Given: To determine 3-Bromocyclohexene is a secondary halide, and benzyl bromide is a primary…

Q: 1.1 Consider the following Friedel-Craft's reaction of the type shown in page 438, Fig 11.3.,…

A: Let us study the mechanism.

Q: 3. What product would you expect to obtain from a nucleophilic substitution reaction of (S)-2-…

Q: 4) Provide the structure of the major organic product of the reactions below. (CH;CH,),N NaOCH CH,…

A: In this question, we want to draw the structure of major product. Reagent and starting material are…

Q: 6. Provide a total synthesis for the target molecule starting from benzene using any reagents…

A: (a) When acetone is treated with phenyl magnesium Bromide (Grignard reagent) then 2-phenyl -2-…

Q: In not more than three (3) sentences, explain why terminal alkynes are acidic.

A: Since you have asked multiple question, we will solve the first question for you as per our…

Q: The following Friedel-Crafts Alkylation reaction usually results from the disubstituted product from…

Q: Give the relative rates of reaction of propyl acetate with the four reagents below to give a…

A: Reactivity depends on the polarity of bonds. The higher the polarity, the more will be the…

Q: Although dehydrohalogenation occurs with anti periplanar geometry,some eliminations have syn…

A: The given chemical reaction is,

Q: 3) Write a detailed mechanism of: CH. CH HNOT HYSO! "NO.

A: Given is the reaction between Toluene in presence of nitric acid and sulfuric acid.

Question

100%

2. Predict the major product of Friedel-Crafts alkylation reaction using the following alkyl
chlorides. Write the mechanism for each of the reaction.
a) CH;CH CH2CI
b) CH:(CH3) CCH CI
e) (CH3) CHCH CI

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps with 1 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Protection of Groups in Organic Synthesis

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Draw the major organic product you would expect to isolate from the reaction of p-bromoethoxybenzene with a misture of HNO3HNO3 and H2SO4H2SO4.
Explain the Summary of Alkyl Halides and SN1, SN2, E1, and E2 Mechanisms ?
Nitrating methyl benzoate. 1.Describe the mechanism of EAS clearly and in detail 2. What is the effect of subtituent of the outcome of EAS；include 3 classes of subtituents
3-Bromocyclohexene is a secondary halide, and benzyl bromide is a primary halide. Both halides undergo SN1 substitution about as fast as most tertiary halides. Use resonance structures to explain this enhanced reactivity.
What is the best way to turn benzene into the following product? Would friedel-crafts alkylation followed by some sort of nitration work or would that be too low yield?
Please explain the mechanism for the Replacement of OH by halogen in reaction with HCl or HBr (SN1 in case of 2° and3° alcohols)
The formation of biphenyl from benzene ring as shown below takes place using Friedel-Crafts alkylation. TRUE OR FALSE
2. In not more than three (3) sentences, explain why terminal alkynes are acidic.3. What impurities are removed when acetylene gas is made to pass through an acidifiedsolution of CuSO4?4. Explain the difference in the rate of free radical bromination reactions of toluene and cyclohexane.
How many distinct alkene products are possible when the alkyl iodide below undergoes E2 elimination?
The two Grignard reactions and the reduction reaction below are all believed to have similar mechanisms. Use the curved arrow formalism to draw a single mechanism for these reactions using :Nuc-1 to indicate the nucleophile. The reacations are: cyclohexylmagnesium chloride + acetone in ether --> 2-cyclohexyl-2-propanol phenylmagnesium bromide + acetone in ether --> 2-phenyl-2-propanol Acetone + NaBH4 --> 2-propanol
i. When But-1-ene (CH3CH2-CH=CH2) is treated with HBr in the presence of a peroxide, give the name and structure of the product. ii. Give the structure of the product from the reaction of propanal with 1M ethanol in dry acid. iii. What happens when Further 1M of ethanol is added to above (ii) ?
The carbocation electrophile in a Friedel-Crafts reaction can be generated in ways other than by reaction of an alkyl chloride with AlCl3. For example, reaction of benzene with 2-methylpropene in the presence of H3PO4 yields tert-butylbenzene. Draw a structure for the electrophile.