2. Warburg assumed that cancer cells required fermentative glucose metabolism due to mitochondrial dysfunction. This notion has since been largely proven incorrect. Instead, there have been a number of proposed rationales as to how the Warburg effect/aerobic glycolysis supports (cancer) cell proliferation. Identify and explain two such hypotheses and why they may not serve as complete mechanistic explanations. Limit your responses to 4 sentences per hypothesis. -it allows cancer cell to make biosynthetic building blocks (nucleotide, lipid, amino acid) more efficiently. -increased demand for NAD+ drives aerobic glycolysis.

2. Warburg assumed that cancer cells required fermentative glucose metabolism due to mitochondrial dysfunction. This notion has since been largely proven incorrect. Instead, there have been a number of proposed rationales as to how the Warburg effect/aerobic glycolysis supports (cancer) cell proliferation. Identify and explain two such hypotheses and why they may not serve as complete mechanistic explanations. Limit your responses to 4 sentences per hypothesis. -it allows cancer cell to make biosynthetic building blocks (nucleotide, lipid, amino acid) more efficiently. -increased demand for NAD+ drives aerobic glycolysis.

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter4: Cells

Section: Chapter Questions

Problem 11TYK

See similar textbooks