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- A colleague e-mails you saying that she has identified an interesting chromosome variation at 21q13. In discussing this discovery with a friend who is not a cytogeneticist, explain how you would describe this location, defining each term in the chromosome address 21q13.Variations in Chromosome NumberAneuploidy Describe the process of nondisjunction and explain when it takes place during cell division.Assume that a meiotic-nondisjunction event causes trisomy 8 in a newborn. If two of the three copies of chromosome 8 are absolutely identical, at what point during meiosis did the nondisjunction event take place?
- In a turtle species, a diploid cell in the G1 phase of the cell cycle contains 22 picograms of DNA (picogram is a measure of the total mass of the DNA present). How much DNA is present in a cell of the same species at prophase II of meiosis (prophase of the second meiotic division)?Rice has a chromosome number of 2n = 24. If different aneuploids are available in rice, identifythe specific aneuploidy that shows the following chromosomal configurations at diakinesis ormetaphase I. Also provide the formula and chromosome number of the different aneuploids. Complete the table. Chromosome configuration at diakinesis or metaphase I Specific Type of Aneuploidy Formula (e.g. 2n+1) Chromosome number (2n=24) Types of gametes n, n+1, n+2, n-1, n-2) a. 1 III + 11 II b. 1 IV + 11 II c. 1 I + 11 II d. 11 II e. 2 I + 10 IIThe garden pea (Pisum sativum) is normally a diploid and has 7 chromosomes in one set (in other words, n = 7). Use this information to answer the following questions: a. How many centromeres would be in a cell of a tetraploid pea plant? ______ b. How many total chromatids would be in a cell of a tetraploid pea plant in metaphase of mitosis? _______ c. How many total chromosomes would be in a cell of a pea plant that is monosomic for a single chromosome?
- During metaphase I of meiosis, tetrads align along the metaphase plate independently of each other. Therefore, there is a random “shuffle” of maternal and paternal chromosomes in the resulting gametes.The following diagram demonstrates how this works in a diploid cell with four chromosomes (2n=4) . Because there are two pairs of chromosomes and each pair can align in one of two ways during metaphase I, the number of possible variations in the gametes produced is 22 or 4.For an organism that is , there are three pairs of chromosomes, so the number of possible variations in the gametes produced due to independent assortment in metaphase I is 23 or 8. In an organism with a haploid number of 7, how many possible combinations of maternal and paternal chromosomes can occur in its gametes? a. 72=49 b. 27=128 c.17=1 d. 214=16 384A diploid individual is heterozygous for a chromosome rearrangement. The original chromosome and its rearranged homolog have the following segments, where ∙ represents a centromere: A B ∙ C D E F G A B ∙ C F E D G While paired in prophase I, a single crossing-over occurs between segment E and segment D of the paired chromosomes. Describe the unusual crossing-over structure that forms as a result.What gamete types will result from crossing over when meiosis is complete? please asapAssume that the diploid number of a certain species is four chromosomes, two large and two small (2n=4). a) Of the following figures, which represents a 3n (triploid) cell in mitotic metaphase? b) For each of the wrong answers from part (a) above, explain briefly why it cannot represent a triploid cell in mitotic metaphase.
- A diploid species has 3 pairs of chromosomes in its somatic cells. In males, the first pair is large submetacentric[1]; the second is medium acrocentric[2], and the third is small telocentric[3]. In females, the first two pairs are like those of the males while the third is large metacentric[4][5], with satellite4 Illustrate the karyograms (drawing/picture of the chromosome) of the following: A triploid cell in females tetrasomic cell in males tetraploid cell in females [1] submetacentric --centrosome is just above the middle of the chromosome [2] acrocentric --centrosome is much higher location than submetacentric so that the “p” arm of the chromosome is much shorter than the q arm [3] telocentric --the centromere is at the end of the chromosome [4] metacentric --centrosome is in the middle of the chromosome; thus the “p-arm” and the “q-arm” or both arms of the chromosome are equal in length [5] satellite-a constriction in an arm of a chromosome, aside…A woman with no phenotype is known to have a 14:21 translocation. 1. With respect to only chromosomes 14 and 21, how many distinct chromosome combinations will happen in her eggs? What portion will be viable? 2. If she has children with a normal man (no translocations), what is the probability that they have a daughter with Down Syndrome or a son with no phenotype?The kidney bean plant, Phaseolus vulgaris, is a diploid speciescontaining a total of 22 chromosomes in somatic cells. Howmany possible types of trisomic individuals could be producedin this species?