3, Suggest reactions to accomplish the following transformations in the forward synthesis direction. Provide rational for the stereoselectivity for relevant transformations. А. OH HO HO OH но В. (2) С. OMe HO, (±)
Q: Br, A Provide an acceptable synthesis for the following 1 SAI 2) Gon all
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Q: Me N. Meo OMe MeN- MeN- H...) -N- MeN- Br MeCN, 100 °C NaH, THF; Br H then 6M HCI MeO2C, -Me Me…
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Q: 18. Suggest a plausible mechanism with structures of the following reaction: Br, H,0 CH3 CH2B.…
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Q: + NG CusO.SH,O MC
A: Detail mechanism is shown below
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Q: 1. State the effects of substituents on a benzene derivative towards further aromatic substitution.…
A: Since you have posted multiple questions, we are entitled to answer the first only.
Q: 7. Supply the structures of compounds in the following reaction sequence : NaCN NaOH SOCI2 Br…
A: From the given reactant to the product E is shown below.
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A: We have to suggest mechanism for the following reaction in step 2
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A: According to Markonikov's addition, the more electronegative part goes to the more substituted C in…
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A: From given The reaction is drawn completely along with structures in the empty boxes and…
Q: write mechanism step by step for the reaction ?
A: The mechanism for the given reaction can be drawn as.
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Q: Propose a detailed, step-wise mechanism for the following transformation, make sure to SHOW all…
A: Desulfonation reaction In organic chemistry, the desulfonation reaction is the hydrolysis of…
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Q: Draw the major organic product(s) generated in the reaction below. Pay particular attention to…
A: Welcome to bartleby ! As per company rules we can't answer more than one question per session . So,I…
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Q: Which of the alkenes below is the most reactive towards acid-catalyzed hydration?
A: Markovnikovs rule is applied to acid catalysed hydration of alkene.
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Q: NaBH, H+ agua CH,OH H,0 H+ Ag,0 1) H+ 2) NH, OH-
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Q: POD 9: 02-10-21 Provide the Stepwise synthesis for the following transformation
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Q: 1. State the effects of substituents on a benzene derivative towards further aromatic substitution.…
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A: Here we have prepare the following compounds by two retrosynthesis pathway
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Q: Give the major organic product(s) of each of the following reactions or sequences of reactions. Show…
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- For butenafine, develop a synthesis that starts with napthalene and benzene. (aromatic methyl groups can be converted to alkyl bromides using Br2/light, and aldehydes by heating the alkyl bromide in DMSO, eg. ArCH3 to ArCH2Br then to ArCHO).2-diazoclyclohexanone undergoes an interesting example of the Wolff rearrangement in methanolic solution. Suggest a mechanism for this reaction.Give the mechanism and product for the reaction below.
- The reaction of 1-iodopropane with potassium thiocyanate (KSCN) in certain solvents results in the formation of two isomeric products, propylthiocyanate and propylisothiocyanate (see scheme below), via the SN2 reaction mechanism. Attempts to prepare a similar mixture of these same isomeric products (propylthiocyanate and propylisothiocyanate) starting from 1-propene is illustrated below. Despite the strong acidity of thiocyanic acid (recall pKa = 1.1), this addition reaction does not lead to either of the products indicated. Based on your knowledge of alkene addition reactions, explain this experimental result.Give the reagents and conditions to provide the following transformations, usethe 1. 2. etc. notations as appropriateShow stereo chemistry and possible outcomes and the steps for the reaction.
- Predict the final product(s) obtained when (2R,3R)-2-bromo-3-methylpentane is subjected to the following sequence of reactions, briefly explaining your rationale. For each step, provide the stepwise mechanism and the regiochemical and stereochemical details as relevant. 1. NaOC2H5/C2H5OH, heat 2. BH3, THF 3. H2O2, OHProvide the missing reagents to complete the reactions below, if there is more than one step required, be sure to indicate appropriately.we know that ethers, such as diethyl ether and tetrahydrofuran, are quite resistant to the action of dilute acids and require hot concentrated HI or HBr for cleavage. However, acetals in which two ether groups are linked to the same carbon undergo hydrolysis readily, even in dilute aqueous acid. How do you account for this marked difference in chemical reactivity toward dilute aqueous acid between ethers and acetals?
- 3 Give mechanisms for the acid-catalyzed and base-promoted alpha-halogenation ofketones. Explain why multiple halogenations are common with basic catalysis andgive a mechanism for the haloform reactionpredict the main product for the addition of 1 equivalent of HX to the following compounds and write the mechanism of the reactionPropose mechanisms compatible with 1) and 2) of the following reactions.