35.36.37.38.Predict the major product from the following intramolecular Aldol addition and itsdehydration product.ilHPredict the major product from the following intramolecular Michael addition.K+-OHH₂OCH₂CH₂O +KCH₂CH₂OHShow the product from each step in the sequence of reactions from ethyl acetoacetic ester.OCH3K+ OHH₂OHPredict the major product from the following Claisen Condensation.K* -OHH₂O, heatH₂O, HheatOCH3CH₂O+KCH₂OHCH₂CH₂O*KCH₂CH₂OHheatH₂O, H+heat

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Answered: 35. Predict the major product from the…

35. Predict the major product from the following intramolecular Aldol addition and its dehydration product. K* -OH H₂O K* -OH H₂O, heat

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter8: Haloalkanes, Halogenation, And Radical Reactions

Section: Chapter Questions

Problem 8.32P

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Concept explainers

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.

Question

35.
36.
37.
38.
Predict the major product from the following intramolecular Aldol addition and its
dehydration product.
il
H
Predict the major product from the following intramolecular Michael addition.
K+-OH
H₂O
CH₂CH₂O +K
CH₂CH₂OH
Show the product from each step in the sequence of reactions from ethyl acetoacetic ester.
OCH3
K+ OH
H₂O
H
Predict the major product from the following Claisen Condensation.
K* -OH
H₂O, heat
H₂O, H
heat
OCH3
CH₂O+K
CH₂OH
CH₂CH₂O*K
CH₂CH₂OH
heat
H₂O, H+
heat

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