5. Rank the following according to increasing reactivity (1- least reactive, 4 – most reactive in a nucleophilic acyl substitution reaction. Briefly explain your answer: bor H3C H3C H3C H3C HO, Cank Explanation

Q: SCH3 OCH3 Br N(CH3)2 1 2 3 A) 3>1> 2>4 B) 3> 2>1>4 C) 4 > 2 > 3 >1 D) 1>3> 2 > 4

A: Order the carboxylic acid derivatives from most reactive to least reactive towards nucleophilic…

Q: may use any other reagents necessary, as long as the starting material is incorporated into the…

A:

Q: This is Wittig Rxn:  Whatever mechanism you choose to draw is fine since you can leave the base as…

A: Wittig reaction is carried out between aldehyde or ketone and ylide to form the alkene .

Q: B. In each of the following pairs, circle the species that is more reactive toward nucleophilic…

A: We know that greater electrophilicity of  the carbonyl, then faster will be the nucleophilic attack

Q: Which product(s) will be formed preferentially in a base elimination? (1) (2) H KOH, EIOH Br Br (3)…

A: Ans

Q: Q 4: Comparing, Phenol reacts readily than the benzene, so it is a A. nucleophiles B. electrophile…

A: Phenol reacts readily than benzene

Q: 5. Explain why the nitrogen on the molecule on the left below is more reactive as a nucleophile than…

A: Nucleophilicity depands On negative charge density.

Q: Draw a detailed mechanism. For each step of the mechanism, jusiuny what you drew/explain the why…

A:

Q: Rank the following in terms of reactivity towards a nucleophile (1 = least reactive and 4 = most…

A: Electrophiles are reagents that are electron deficient. These attack reagents that are rich in…

Q: Rank the following according to increasing reactivity with 1 as the least reactive, and 4 as the…

A: The reactivity order for nucleophilic acyl substitution is as follows:

Q: ii. butyric acid + sodium chloride 1. React the carbonyl compound: It is (circle one) CONJUGATED…

A: Given: Reaction of Butyric acid with sodium chloride To find: Nucleophile and conjugated or non…

Q: Which benzene derivative would be the most reactive in an electrophilic aromatic substitution…

A:

Q: -Cf3 Nucleophilic Attack

A:

Q: OH HO CH3

A: Any molecule or ion which are electron rich species are called nucleophile for example -NH2,-OH and…

Q: Which benzylic halide reacts faster in an SN1 reaction? Explain.

A: From among the two benzylic halide given we can tell that the halide A reacts much faster than…

Q: Drawing the Products of an SN1 Reaction Label the nucleophile and leaving group, and draw the…

A: the nucleophile and leaving group

Q: Draw the major E2 elimination products from each of the attached alkyl halides.

A: E2 elimination stаnds fоr bimоleсulаr eliminаtiоn. The reасtiоn invоlves а оne-steр meсhаnism in…

Q: final product. b) Draw the correct first step and complete the mechanism, showing the structure of…

A: (a) The given mechanism is incorrect. The carbonyl oxygen of formaldehyde is not that much basic…

Q: When an electrophilic aromatic substitution reaction on naphthalene is reversible, such as in a…

A: The major product of the reaction has to be given,

Q: Arrange the following compounds in order of decreasing reactivity for a nucleophilic substitution…

A: We have to find out the reactivity for a nucleophilic substitution reaction

Q: Explain why quinuclidine is a much more reactive nucleophile than triethylamine, even though both…

A:

Q: Rank the following substrates’ ability to undergo nucleophilic aromatic substitution when treated…

A: In a nucleophilic substitution reaction, first step is the nucleophilic attack on the electron…

Q: Explain why quinuclidine is a much more reactive nucleophile thantriethylamine, even though both…

A: The chemical species that donates a pair of electron to form a chemical bond is called a…

Q: In the reaction shown below draw curly arrows to show how the acetylide can act as a nucleophile.

A: The following steps are involved in the attack of acetylide as a nucleophile over acetone: The…

Q: Consider the following groups of compounds. In each series circke the weaker (poorer) nucleophile.…

A: The nucleophilicity of a substrate depends upon many factors such as basicity, nature of…

Q: 2. A chemist wishes to perform the nitration of methyl benzoate as follows: HNO3, H2SO4 Draw a…

A:

Q: Draw a stepwise, detailed mechanism for the following reaction.

A: In intramolecular reactions, the reactive sites are present in the same molecule. The simplest…

Q: a. Strong bases are [ Select ] nucleophiles. b. Electron-withdrawing groups nearby a nucleophilic…

A: Bases try to abstract hydrogen whereas nucleophiles attack electron deficit carbon atoms. The groups…

Q: Draw the resonance interaction that lessens the electrophilicity of the carbonyl using the structure…

A:

Q: Indicate which of the ff. statements regarding nucleophilicity is incorrect. 1. F- is more…

A: Nucleophilicity is directly proportional to Polarisability.  Order of nucleophilic halide :…

Q: 9. Rank the following nucleophiles, in a solution of DMF, in order of weakest to strongest. НО CI…

A: DMF is a solvent known as dimethylformamide. It is a polar aprotic solvent. It doesn’t form hydrogen…

Q: Rank the following species from best nucleophile to poorest nucleophile in the given solvent: OH A B…

A: Nucleophilicity is determined by the tendency to donate the electron pair. The species which carry…

Q: F3C² CF₂ reactive acyl Most -nucleophilic اعم least substitution H3C reactive CH3 3 to word

A: Dear student since you have asked multiple questions but according to guidelines we will solve 1st…

Q: d. Hint: the acetylide ion is both a strong base and a strong nucleophile. Br Na+ ECH THF

A: given substrate is a one degree alkyl bromide and it will go elimination and substitution reaction…

Q: Sn2, E2  E1cb  Sn1, E1 (anti)  E2, E1cb  Sn1, E1   2 steps poor leaving group 2 carbons…

A: Primary halides with strong nucleophiles prefer to form SN2 products. Branched halides with a strong…

Q: Rank the nucleophiles in each group in order of increasing nucleophilicity. a.−OH, −NH2, H2O b.−OH,…

A: a. Negatively charged nucleophiles are stronger nucleophiles than neutral ones. Hence water is the…

Q: Consider the reaction of an alkyl bromide and hydroxide ion. Br HO- Draw the Sy1 product. Draw the…

A: SN1 reaction is unimolecular nucleophilic substitution reaction. It is a two step reaction and the…

Q: Rank the following compounds towards nucleophiles.  (1-most reactive - 4- least reactive)

A: The most reactive nucleophile among the following is  More the number of attached methyl / Ethyl…

Q: Rank the nucleophiles in following group in order of increasing nucleophilicity. −OH, Br−, F− (polar…

A: The given groups are -OH, Br-, F- To find: The increasing order of nucleophilicity

Q: Q.2). How will you compare briefly the reactivity of Pyridine and 2-methoxy Pyridine with Furan also…

A: Have a look at the resonance structures of Pyridine and Furan     As we can see in the above…

Q: This reaction is an example of conjugate addition of a nucleophile to an a,ß-unsaturated carbonyl.…

A: The alpha hydrogen to the carbonyl group is acidic in nature and this hydrogen is removed in…

Q: Which position will an electophile (E*) most likely add in an Electophilic Aromatic Substitution…

A:

Q: Draw a stepwise, detailed mechanism for the following intramolecular reaction.

A: The intramolecular ring closure is carried out in the presence of strong acid like H2SO4. The acid…

Q: 1. Rank the following according to increasing reactivity (1 - least reactive, 4 - most reactive in a…

A:

Q: b. Rank by rate of electrophilic aromatic substitution. The compound that reacts the fastest in an…

A: The answer is given below:

Q: Determine whether each nucleophilic acyl substitution is likely to occur.

A: Nucleophilic Substitution reaction:  When a nucleophile attacks an electron deficient center also…

Q: For succeeding items, refer to the image provided. A B CH3C=N 1. Which atom will most like be the…

A: In organic chemistry, there are species that are either electron-rich or electron-deficient.…

Q: Draw the neutral organic product expected under these reaction conditions. Select Draw Rings More…

A:

Q: Rank the nucleophiles in each group in order of increasing nucleophilicity.a. -OH, -NH2, H2Ob. -OH,…

A: Nucleophilicity increases with increase in basicity of species.  Across a period from right to left…

Stereochemistry and Isomerism

Stereochemistry deals with the three-dimensional structure and properties of molecules. It explains the arrangement of atoms and their manipulation within a molecule in a 3D structure. Stereochemistry can be dealt with all types of molecules. Based on the stereochemistry of a molecule, the physical and chemical properties of the molecules vary.