5.46 Locate the stereogenic centers in each drug. NH2 H a. N. N- но HO amoxicillin (an antibiotic) OH b. OHO- HO norethindrone (oral contraceptive component) с. Beuio N. heroin (an opiate)

Q: 15.36 Phenylethylamine is a natural substance that is structurally similar to amphetamine. It is…

A: The two-step synthesis reaction is given as follows;

Q: What product is formed when acetic acid is treated with each reagent: (a) CH3NH2; (b) CH3NH2, then…

A: a.

Q: a.Label the four stereogenic centers in sorbitol as R or S. b.How are sorbitol and A related? c. How…

A: A carbon atom that has four different atoms or groups bonded to it is known as a chiral carbon and…

Q: Locate the stereogenic centers in attached drug.

A:

Q: dentify the organic functional groups and reaction type for the following reaction. The reactant is…

A: D-Glucose contains two isomeric forms one is alpha and the other is beta. Pyranose ring is formed by…

Q: In the structure of Simvastatin as shown below, determine the configuration of the carbon atoms with…

A: Assign priority (1-4) of the stereocentre of the carbon.

Q: (a) Draw the more stable chair form of fucose, an essential monosaccharide needed in the diet and a…

A: Fucose if Deoxy and L-monosacharride unlike other naturally occurring monosachharides.

Q: Captopril is a drug used to treat high blood pressure and congestive heart failure. a.Designate each…

A: Chiral center: A carbon atom attached with 4 different atoms or groups  To find R and S…

Q: I. a) Draw the structure of the products that form upon complete hydrolysis (both aq HCl and aq NaOH…

A:

Q: (a) Convert each cyclic monosaccharide into a Fischer projection of its acyclic form. (b) Name each…

A: Black colored atoms have four bonds.  So these are the carbon atoms.  The grey colored balls have…

Q: Locate the stereogenic centers in each drug. NH2 H OH C=C-H а. b. HO CH3 COOH amoxicillin…

A: The stereogenic center is the carbon in the compound where all four groups attached will be…

Q: The following trisaccharide derivative is important to human health. The A ring is ?-deoxy? но но-…

A: In numbering of cyclic ether start numbering  from that side where substituent is near.

Q: Neuroprotectin D1 (NPD1) is synthesized in the body from highly unsaturated essential fatty acids.…

A: When two bulky groups on each doubly bonded carbon are on same side, then the alkene is cis or Z…

Q: Draw the structure of (S,S)-ethambutol, a drug used to treat tuberculosis that is 10 times more…

A: Detail drawing procedure of (S,S)-ethambutol in zigzag manner is given below

Q: (a) Convert each cyclic monosaccharide into a Fischer projection of its acyclic form. (b) Name each…

A: If two diastereomers having more than one chiral centers differ in absolute configuration at one…

Q: Saquinavir (trade name Invirase) is a protease inhibitor, used to treat HIV(human immunodeficiency…

A: Chirality: It refers to a Carbon atom in a molecule that contains four different substituents. R and…

Q: B4. OH H CH₂OH H OH H H OH H O H Lactose CH₂OH H OH H H ОН H OH но, НО. H REXEL H H HO O OH OH H H H…

A: The question asks us to find some structural differences in lactose and sucrose.

Q: (a) Locate the stereogenic centers in the ball-and-stick model of lisinopril, a drug used to treat…

A:

Q: Consider the tetrasaccharide stachyose drawn below. Stachyose is found in white jasmine, soybeans,…

A: Since we only answer up to 3 sub-parts, we’ll answer the first 3. Please resubmit the question and…

Q: (a) Draw the more stable chair form of fucose, an essential monosaccharide needed in the diet and a…

A: The Fisher projection is drawn by converting the stable staggered conformation into less stable…

Q: 7.70 Quinapril (trade name Accupril) is used to treat high blood pressure and congestive heart…

A: Diastereomers are non mirror image and non identical stereoisomers

Q: Draw a stepwise mechanism for the following isomerization.

A: A stepwise mechanism for the given isomerization can be drawn as

Q: Monosaccharide A is a diastereomer of d-lyxose. Treatment of A with nitric acid forms an optically…

A: First, the D-lyxose is shown as below by using Fischer projection. For given compound the structure…

Q: Monosaccharide Structure and Stereochemistry For D-arabinose: Draw an epimer at C3.

A: To find: C3 epimer of D- arabinose

Q: Draw the products formed (including stereoisomers) when each compound is reduced with NaBH4 in…

A: (a) The given compound is,

Q: (S)-Lactic acid has a specific rotation of +3.8. (a) If the ee of a solution of lactic acid is 60%,…

A: This is a measurement to understand that which enantiomer of a compound is predominant.

Q: ECONa Is the reachch SN1,SN2 E1 or ez and wnat is the majar product. Et OH

A:

Q: Draw all possible constitutional isomers of a triacylglycerol formed from one mole each of palmitic,…

A: Triacylglycerols (triglycerides) are the lipids formed by the reaction of glycerol and fatty acids.

Q: Page но. H CHO quinine (antimalarial drug a Calculate the ee of a solution with the following (a)…

A: Given: “Since you have posted a question with multiple sub-parts, we will solve the first three…

Q: Saquinavir (trade name Inclrase) belongs to a class of drugs called protease Inhibitors, which are…

A: stereogenic centers are optically active centers.

Q: oue Matchthe tollowing cleavage with ithe corre. ct goro lucts. 1 Eth CH eth

A:

Q: 5.66 A mixture contains equal amounts of compounds A-D. A B C D a. Which compounds alone are…

A: A,B,C,D are four compounds.The asteric mark(*) indicated for chiral centre in the below structures.

Q: Locate the stereogenic centers in attached drug.

A: Those carbons having four different groups or substituents attached are called as stereogenic…

Q: Monosaccharide A is a D-aldotetrose. Treatment of A with nitric acid gives an optically inactive…

A:

Q: Identify F in the following reaction sequence. F was converted in several steps to the…

A: Firstly, the oxygen atom of the -OH group will attack the sulfur atom of methanesulfonyl chloride…

Q: The following trisaccharide derivative is important to human health. The A ring is ?-deoxy? но- но…

A: Deoxy sugar is sugar in which hydroxy group is replaced by hydrogen.

Q: A D-aldopentose A is oxidized to an optically inactive aldaric acid with HNO3. A is formed by the…

A: solution;-

Q: Which heteroatom don't contain heterocyclic compounds? a. Phosphorus b. Oxygen c. Nitrogen d. Sulfur

A: The heterocyclic compounds are ring compounds containing  heteroatom  such as oxygen, nitrogen,…

Q: a. Draw a three-dimensional structure for the following steroid. b. What is the structure of the…

A: a. In 3D structure, each color represent a specific atom and each line represents each bond present…

Q: Draw a stepwise mechanism for the attached isomerization.

A: A stepwise mechanism for the attached isomerization is given below:

Q: 5.66 A mixture contains equal amounts of compounds A-D. a D B A a. Which compounds alone are…

A:

Q: a. Which structure(s) contain(s) sphingosine? b. Which structure(s) is a (are) glycolipid(s)? c.…

A: 1) Sphingosine (2-amino-4-trans-octadecene-1,3-diol) is an 18-carbon amino alcohol with an…

Q: Draw all constitutional isomers formed when X is treated with NBS + hv.

A:

Q: Consi der the structures of glycme and betaine Cor trimethylglycıne) below, Hが、。 betain glyeine a) J…

A:

Q: What product is formed when each compound is treated first with LDA in THF solution at low…

A: LDA ( Lithium diisopropyl amide) is a strong base. It abstract the acidic proton from the compound…

Q: There is a tick and mosquito repellent DEET (diethyltoluamide) that is prepared by a reaction of…

A: The reaction used here is amide formation reaction by carboxylic acid and amine (secondary) under…

Stereochemistry and Isomerism

Stereochemistry deals with the three-dimensional structure and properties of molecules. It explains the arrangement of atoms and their manipulation within a molecule in a 3D structure. Stereochemistry can be dealt with all types of molecules. Based on the stereochemistry of a molecule, the physical and chemical properties of the molecules vary.