7. A 24-year-old schizophrenia patient with prominent cognitive symptoms and social impairment is being evaluated for treatment. Her care provider is considering initiating ziprasidone, quetiapine, or aripiprazole, all of which share the property of serotonin 1A agonism. This receptor binding property is expected to have clinical effects in schizophrenia most similar to: A. Dopamine 2 antagonism 1 B. Histamine 1 antagonism 1 C. Serotonin 2A antagonism 1 D. Serotonin transporter blockade

7. A 24-year-old schizophrenia patient with prominent cognitive symptoms and social impairment is being evaluated for treatment. Her care provider is considering initiating ziprasidone, quetiapine, or aripiprazole, all of which share the property of serotonin 1A agonism. This receptor binding property is expected to have clinical effects in schizophrenia most similar to: A. Dopamine 2 antagonism 1 B. Histamine 1 antagonism 1 C. Serotonin 2A antagonism 1 D. Serotonin transporter blockade

Essentials of Pharmacology for Health Professions

7th Edition

ISBN:9781305441620

Author:WOODROW

Publisher:WOODROW

Chapter20: Psychotropic Medications, Alcohol, And Drug Abuse

Section: Chapter Questions

Problem 12CRQ

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The drug Rohypnol ("roofies") acts as a sedative. What is the mechanism by which roofies act in the brain? A. Roofies act at the GABA receptor complex which opens a sodium channel B. Roofies act at the acetylcholine receptor C. Roofies act as a dopamine receptor agonist D. Roofies block the dopamine transporter E. Roofies act at the GABA receptor complex which opens a chloride channel
2. If we assume that amygdala-dependent learning uses the same LTP mechanism as the hippocampus, what would likely happen if an NMDA receptor antagonist (blocker) was infused bilaterally a mouse's amygdala? a. It will not be able to experience nor express the emotion of happiness b. It will be unable to learn new declarative information c. It will be unable to learn new motor skills d. It will be unable to undergo fear conditioning e. It will be unable to learn to press a lever to receive a reward
Cocaine addiction occurs whena. cocaine binds to dopamine transporter proteins on the presynaptic membrane.b. the numbers of postsynaptic dopamine receptors are reduced in limbic system nerve cells. c. neurotransmitter levels rise in lymbic system synapses.d. dopamine transporters become disabled.
5. What can happen as a result of excessive dopamine blockage? 6. Atypical antipsychotics block which receptors?
7. Both classes of antipsychotics bind nonspecifically to other receptors in the body aside from dopamine and serotonin. Why is this a problem? 8. List the examples of antipsychotic drugs (both conventional and atypical)
psychoactive compounds in cannabis act on the CB1 receptor, the endocannabinoid that binds to this receptor is called: Select one: a. nitric oxide b. a Gi protein c. anandamide d. THC e. all of theses are endocannabinoids.
Monoamine oxidase inhibitors are sometimes used in the treatment of Parkinson’s disease. What is their mechanism of action? a. They inhibit the breakdown of dopamine. b. They inhibit the reuptake of dopamine by glia. c. They inhibit the reuptake of dopamine by neurons. d. They inhibit the synthesis of norepinephrine from dopamine. e. They inhibit the synthesis of dopamine.
1. The blood-brain barrie effectively prevents all drugs from entering the nervous system. True or false 2. Many common antidepressants work by preventing the release of serotonin. True or false 3. Drugs may influence the activity or amount of neurotransmitters. True or false 4. Painkillers like morphine raise levels of serotonin and noradrenaline. True or false 5. Cocaine creates feeling of euphoria by: flooding the neural network with dopamine and serotonin. Depleting the neural network of dopamine and serotonin.
7. Which statement describes the sympathetic nervous system? A. Stimulation of the sympathetic nervous system generally causes a decrease in blood pressure. B. The nerves exit the central nervous system in the head and from the lumbar spine. C. The only neurotransmitters it secretes are epinephrine and norepinephrine. D. There are three different subtypes of adrenergic receptors on target organs.
The behaviours associated with cocaine use mimic some of the symptoms of schizophrenia because: Question 53 options: a) Cocaine increases serotonergic transmission in the prefrontal cortex b) Cocaine increases dopamine binding at D2 receptors in the mesocortical tract c) Cocaine increases the reuptake of serotonin in the tuberoinfundibular tract d) Cocaine decreases dopamine binding at D2 receptors in the nigrostriatal tract
Q. Barbiturates inhibit my Reticular Activating System (RAS), therefore what effect do they have on my body? A) Increased awareness B) Muscle tension C) Increased seizures D) Reduced consciousness .
2) When Epinephrine binds to alpha and beta receptor sites in the body, it causes a reaction whichincreases vasoconstriction and heart contractility. The term used to define Epinephrine's stimulation of the receptor is ____________________. A) Therapeutic B) Agonist C) Adverse D) Antagonist