7. Pick two of the following compounds, and provide a synthetic scheme to produce the following compounds starting from benzene, using any inorganic material, and any organic material with 4 carbons or less. If you have produced a compound, you can use that compound in subsequent work without showing its synthesis again. NH2 H,C. CH, OH NH2 CH3 CH, CH, a) b) H3CO d) H,C

7. Pick two of the following compounds, and provide a synthetic scheme to produce the following compounds starting from benzene, using any inorganic material, and any organic material with 4 carbons or less. If you have produced a compound, you can use that compound in subsequent work without showing its synthesis again. NH2 H,C. CH, OH NH2 CH3 CH, CH, a) b) H3CO d) H,C

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter21: Nas: Nucleophilic Aromatic Substitution

Section: Chapter Questions

Problem 7E

See similar textbooks

Similar questions

(19, 8, 2) Specify a synthetic scheme that would produce the compound shown above in the fewest steps possible. Use one of the starting materials shown together with any of the available reagents. Give the number of the starting material followed by the letters of the reagents in the order of their use, for example: 3be.
For butenafine, develop a synthesis that starts with napthalene and benzene. (aromatic methyl groups can be converted to alkyl bromides using Br2/light, and aldehydes by heating the alkyl bromide in DMSO, eg. ArCH3 to ArCH2Br then to ArCHO).
Draw the major organic product you would expect to isolate from the reaction of p-bromoethoxybenzene with a misture of HNO3HNO3 and H2SO4H2SO4.
Benzene, C6H6 undergoes substitution reaction with concentrated nitricacid, HNO3 to produce compound L. The reaction of compound L withbromine, Br2 in the presence of iron tribromide, FeBr3 produced compoundM. Benzene also undergoes Fridel-crafts alkylation reaction withchloroethane, CH3CH2Cl using catalyst N to produce compound P (i) Draw the structural formula of L, M and P (ii) State catalyst N. (iii) Show the formation of electrophile that will be reacted with benzene for theformation of compound P.
A key step in the synthesis of naproxen, an NSAID more commonly known by its brand name, Aleve (Section 3.9), is a coupling reaction of 2-bromo-6-methoxynaphthalene to form 2-methoxy-6-vinylnaphthalene. Show three different coupling reactions, and the required reagents, that could be used tocarry out this step.
we know that ethers, such as diethyl ether and tetrahydrofuran, are quite resistant to the action of dilute acids and require hot concentrated HI or HBr for cleavage. However, acetals in which two ether groups are linked to the same carbon undergo hydrolysis readily, even in dilute aqueous acid. How do you account for this marked difference in chemical reactivity toward dilute aqueous acid between ethers and acetals?
Show stereo chemistry and possible outcomes and the steps for the reaction.
Give the reagents and conditions to provide the following transformations, usethe 1. 2. etc. notations as appropriate
Starting from Benzene explain how compound E could be prepeared. Give reagents, conditions and equations for each step.
The following are intermediate products in the stepwise synthesis of compound 1 from benzene. Give the correct sequence of reactions with the appropriate reagents that will lead to the correct intermediate products and final product.
The following bicyclic ketone has two -carbons and three -hydrogens. When this molecule is treated with D2O in the presence of an acid catalyst, only two of the three -hydrogens exchange with deuterium. The -hydrogen at the bridgehead does not exchange. How do you account for the fact that two -hydrogens do exchange but the third does not? You will find it helpful to build models of the enols by which exchange of -hydrogens occurs.
The Williamson ether synthesis involves treatment of a haloalkane with a metal alkoxide. Following are two reactions intended to give benzyl tert-butyl ether. One reaction gives the ether in good yield, and the other reaction does not. Which reaction gives the ether? What is the product of the other reaction, and how do you account for its formation?