9. Phosphotyrosine (shown below) has four ionizable functional groups (pK1 = 2.5, pKR1= 2.1, pKr2 = 7.2, pK2 = 9.5).(a) Write the equilibrium equation for its four ionization forms and assign the properpka for each ionization. DRAW the structure of phosphotyrosine in each ionizationstate. What is the net charge on the phosphotyrosine molecule in each ionizationstate?*H3N.pk2 - 9.5.COOHpK, - 2.5O=P-OH pKRI - 2.1ÖHpKRI - 7.2(b) Draw the titration curve of phosphorotyrosine and indicate each pKa and theisoelectric point (pl), indicate the molar equivalents of OH on the x-axis.

a) Given is the phosphotyrosine molecule, with four ionizable groups.

Answered: 9. Phosphotyrosine (shown below) has…

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter18: Functional Derivatives Of Carboxylic Acids

Section18.8: Interconversion Of Functional Derivatives

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