A case-control study of patients on antihypertensive drugs related an increased risk of myocardial infarction (MI) for patients using calcium channel blockers. In this study, cases were antihypertensive drug patients who had suffered a first fatal or nonfatal MI through 1993, and controls were antihypertensive drug patients, matched by demographic factors, who had not suffered a MI. Among the comparisons reported were patients receiving calcium channel (CC) blockers (with and without diuretics) and patients receiving B-blockers (with and without diuretics). Results of numbers of patient by drug/MI status combination are given in the following table. Antihypertensive O HO: p1=p2 vs. Ha: p1 < p2 O HO: p1>p2 vs. Ha: p1=p2 Drug Does it appear that an increased risk of myocardial infarction (MI) is related to using calcium channel (CC) blockers? The case-control nature of this study requires we compare the proportion of CC blocker users among those had MI attack (p1) vs. the proportion of CC blocker users among those had no MI (p2). What is your hypothesis for this test? ⒸHO: p1=p2 vs. Ha: p1=p2 CC blocker B-blocker O HO: p1=p2 vs. Ha: p1>p2 Occurrence of Yes (cases) 80 85 Myocardial Infarction No (controls) 230 395

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True or False? We have strong evidence against Ho: P1 = P2 and support the claim that an increased risk of myocardial infarction (MI) is related to using calcium channel (CC) blockers.
Transcribed Image Text:True or False? We have strong evidence against Ho: P1 = P2 and support the claim that an increased risk of myocardial infarction (MI) is related to using calcium channel (CC) blockers.
A case-control study of patients on antihypertensive drugs related an increased risk of myocardial infarction (MI) for patients using calcium channel blockers. In this study, cases were
antihypertensive drug patients who had suffered a first fatal or nonfatal Ml through 1993, and controls were antihypertensive drug patients, matched by demographic factors, who had not
suffered a MI. Among the comparisons reported were patients receiving calcium channel (CC) blockers (with and without diuretics) and patients receiving B-blockers (with and without
diuretics). Results of numbers of patient by drug/MI status combination are given in the following table.
Antihypertensive
O HO: p1=p2 vs. Ha: p1 < p2
O HO: p1> p2 vs. Ha: p1=p2
ⒸHO: p1=p2 vs. Ha: p1 = p2
CC blocker
B-blocker
O HO: p1=p2 vs. Ha: p1 > p2
Occurrence of
Yes (cases)
80
85
Drug
Does it appear that an increased risk of myocardial infarction (MI) is related to using calcium channel (CC) blockers? The case-control nature of this study requires we compare the
proportion of CC blocker users among those had MI attack (p1) vs. the proportion of CC blocker users among those had no MI (p2).
What is your hypothesis for this test?
Myocardial Infarction
No (controls)
230
395
Transcribed Image Text:A case-control study of patients on antihypertensive drugs related an increased risk of myocardial infarction (MI) for patients using calcium channel blockers. In this study, cases were antihypertensive drug patients who had suffered a first fatal or nonfatal Ml through 1993, and controls were antihypertensive drug patients, matched by demographic factors, who had not suffered a MI. Among the comparisons reported were patients receiving calcium channel (CC) blockers (with and without diuretics) and patients receiving B-blockers (with and without diuretics). Results of numbers of patient by drug/MI status combination are given in the following table. Antihypertensive O HO: p1=p2 vs. Ha: p1 < p2 O HO: p1> p2 vs. Ha: p1=p2 ⒸHO: p1=p2 vs. Ha: p1 = p2 CC blocker B-blocker O HO: p1=p2 vs. Ha: p1 > p2 Occurrence of Yes (cases) 80 85 Drug Does it appear that an increased risk of myocardial infarction (MI) is related to using calcium channel (CC) blockers? The case-control nature of this study requires we compare the proportion of CC blocker users among those had MI attack (p1) vs. the proportion of CC blocker users among those had no MI (p2). What is your hypothesis for this test? Myocardial Infarction No (controls) 230 395
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