A case-control study was conducted to evaluate the relationship between physical activity and coronary heart disease (CHD) in men. A total of 406 men newly diagnosed with CHD were included together with 406 men of similar ages who did not have CHD. The risk of CHD (measured by the OR) was higher among men who were inactive or only moderately active (collectively called ‘inactive’) than among those who were physically active: (See attached image) Odds ratio for inactive men compared to active men= (299 x 136)/(270 x 107)=1.41 Suppose there is no misclassification in these data. What would the observed OR have been... 1. If 20% of all the inactive men had been misclassified as active? 2. If 10 % of inactive cases had been misclassified as active?
A case-control study was conducted to evaluate the relationship between physical activity and coronary heart disease (CHD) in men. A total of 406 men newly diagnosed with CHD were included together with 406 men of similar ages who did not have CHD. The risk of CHD (measured by the OR) was higher among men who were inactive or only moderately active (collectively called ‘inactive’) than among those who were physically active:
(See attached image)
Odds ratio for inactive men compared to active men= (299 x 136)/(270 x 107)=1.41
Suppose there is no misclassification in these data.
What would the observed OR have been...
1. If 20% of all the inactive men had been misclassified as active?
2. If 10 % of inactive cases had been misclassified as active?
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