A certain drug binds to a protein with Kd = 850.0 nM. What initial concentration of the drug would you need to add to a 50.0 µM solution of the protein so that 95.0% of the protein molecules are drug-bound at equilibrium? A. 1.62 μM B. 16.2 μΜ C. 47.5 μΜ D. 52.6 μM E. 63.7 μΜ

Chemistry: The Molecular Science
5th Edition
ISBN:9781285199047
Author:John W. Moore, Conrad L. Stanitski
Publisher:John W. Moore, Conrad L. Stanitski
Chapter13: The Chemistry Of Solutes And Solutions
Section13.6: Expressing Solution Composition
Problem 13.9CE
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A certain drug binds to a protein with Kd = 850.0 nM. What initial concentration of the drug would you need to add to a 50.0 µM solution of the protein so that 95.0% of the protein molecules are drug-bound at equilibrium? A. 1.62 μM B. 16.2 μΜ C. 47.5 μΜ D. 52.6 μM E. 63.7 μΜ
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