A chemist synthesizes four new chemical compounds in the laboratory and names them PFI1, PFI2, PFI3, and PFI4. He gives the PFI compounds to a geneticist friend and asks her to determine their mutagenic potential. The geneticist finds that all four are highly mutagenic. She also tests the capacity of mutations produced by the PFI compounds to be reversed by other known mutagens and obtains the following results. What conclusions can you make about the nature of the mutations produced by these compounds? Reversed by Mutations produced by 2- Aminopurine Nitrous acid Hydroxylamine Acridine orange PFI1 Yes Yes Some No PFI2 No No No No PFI3 Yes Yes No No PFI4 No No No Yes
A chemist synthesizes four new chemical compounds in the laboratory
and names them PFI1, PFI2, PFI3, and PFI4. He gives the PFI
compounds to a geneticist friend and asks her to determine their
mutagenic potential. The geneticist finds that all four are highly
mutagenic. She also tests the capacity of mutations produced by the PFI
compounds to be reversed by other known mutagens and obtains the
following results. What conclusions can you make about the nature of
the mutations produced by these compounds?
Reversed by
Mutations
produced
by
2-
Aminopurine
Nitrous
acid Hydroxylamine Acridine
orange
PFI1 Yes Yes Some No
PFI2 No No No No
PFI3 Yes Yes No No
PFI4 No No No Yes
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