Fill the Table with mutagenic agents and provide their type (physical, chemical, biological) and their classification based on their effect (teratogenic, carcinogenic, clastogenic, or non-specific), together with their modes of action. Mutagen Type of Mutagen Classification based on effect Action 2-aminopurine Acridine orange Proflavine
Fill the Table with mutagenic agents and provide their type (physical, chemical, biological) and their classification based on their effect (teratogenic, carcinogenic, clastogenic, or non-specific), together with their modes of action.
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Mutagen |
Type of Mutagen |
Classification based on effect |
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2-aminopurine |
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Acridine orange |
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Proflavine |
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Mutagens are the known sources of physical, chemical or biological triggers of faults through manipulating the genotype or gene expression that contributes to a genetic abnormality, and this process is called a mutation. It can be spontaneously or may be induced by mutagen.
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Mutagen |
Types of mutagen |
Effect of mutagen |
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2-Aminopurine |
Chemical mutagen |
2-Aminopurine, a base analogue mutagen, it causes transition and frameshift mutations. The analogue is cause mutations by two process: directly due to cytosine mispairing, and indirectly, by mismatch repair saturation
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Acridine orange |
Chemical Mutagen |
Acridine orange dye induced mutations are activated by the removal or addition of a base pair, triggering a mutation in the frameshift.
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Proflavin |
Chemical Mutagen |
By polymerizing among nucleic acid base pairs, Proflavine induces basepair deletions or basepair insertions. It can cause the double-stranded DNA breaks in the of light.
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