A clinical trial is run among 40 HIV patients in order to assess the effectiveness of a new anti-retroviral therapy. Patients are randomized. One group received the standard anti-retroviral therapy (usual care) while the other group received the new anti-retroviral therapy. They are monitored for three months. The primary variable is the viral load which represents the number of HIV copies per milliliter of blood. The most appropriate statistical test to determine the significant difference in viral load in patients receiving the standard versus the new anti-retroviral therapy is Mann- Whitney U Test. a.True b.False

A clinical trial is run among 40 HIV patients in order to assess the effectiveness of a new anti-retroviral therapy. Patients are randomized. One group received the standard anti-retroviral therapy (usual care) while the other group received the new anti-retroviral therapy. They are monitored for three months. The primary variable is the viral load which represents the number of HIV copies per milliliter of blood. The most appropriate statistical test to determine the significant difference in viral load in patients receiving the standard versus the new anti-retroviral therapy is Mann- Whitney U Test. a.True b.False

College Algebra (MindTap Course List)

12th Edition

ISBN:9781305652231

Author:R. David Gustafson, Jeff Hughes

Publisher:R. David Gustafson, Jeff Hughes

Chapter8: Sequences, Series, And Probability

Section8.7: Probability

Problem 58E: What is meant by the sample space of an experiment?

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What is an experiment?
In randomized, double-blind clinical trials of a new vaccine, infants were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 126 of 387 subjects in the experimental group (group 1) experienced drowsiness as a side effect. After the second dose, 158 of 574 of the subjects in the control group (group 2) experienced drowsiness as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced drowsiness as a side effect than subjects in group 2 at the α=0.01 level of significance? Verify the model requirements. Select all that apply. A. The sample size is less than 5% of the population size for each sample. B. n1p11−p1≥10 and n2p21−p2≥10 C. The samples are dependent. D. The sample size is more than 5% of the population size for each sample. E. The samples are independent. F. The data come…
An American medical team wishes to test whether passive smoking affects the chance of children contracting bronchitis. Historically, the disease has been known to occur at least once in 20% of children aged 12. The team analysed the results of a random sample of 250 12-year-old children who were passive smokers, and found that 30 of these had contracted bronchitis at least once in their lives. Use a 5% level of significance to test the claim that the proportion of children who are passive smokers is 20%. What is the null and alternate hypotheses What is the value of the test statistic from below z = 3.16 z = -3.16 z =3.89 z = -3.89 What is the p-value from below 0.0016 0.0008 0.0000 0.0001 Based on this evidence, what is the conclusion
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A double-blind, randomized comparative experiment compared the effect of the drug lorcaserin and a placebo on weight loss in overweight adults. All subjects also underwent diet and exercise counseling. The study reported that, after one year, patients in the lorcaserin group had an average weight loss of 5.8 kilograms (kg), while those on the placebo had an average weight loss of 2.2 kg (P < 0.001). Explain to someone who knows no statistics why these results mean that there is good reason to think that lorcaserin works. Include an explanation of what P < 0.001 means.
A 2017 article in The New England Journal of Medicine details the results of a randomized clinical trial designed to evaluate the efficacy of a rotavirus gastroenteritis vaccine designed for infants. As per the authors: “Each year, rotavirus gastroenteritis is responsible for about 37% of deaths from diarrhea among children younger than 5 years of age worldwide, with a disproportionate effect in sub-Saharan Africa. We conducted a randomized, placebo-controlled trial in Niger to evaluate the efficacy of a live, oral bovine rotavirus pentavalent vaccine (BRV-PV, Serum Institute of India) to prevent severe rotavirus gastroenteritis. Healthy infants received three doses of the vaccine or placebo at 6, 10, and 14 weeks of age. Episodes of rotavirus gastroenteritis were assessed through active and passive surveillance.” The following Kaplan-Meier curves show the time to a diagnosis of rotavirus gastroenteritis separately for the vaccine and placebo samples. Infants were followed for up to 60…
In a randomized double-blind clinical trials of a new vaccine children were randomly divided into two groups subjects in group one received the new vaccine while subjects in group 2 received a control vaccine after the second dose 112 of 690 subjects in the experimental group 1 experienced drowsiness as a side effect after the second dose 69 of 571 of the subjects in the control group 2 experienced drowsiness as a side effect does the evidence suggest that a higher proportion of subjects in group 1 experience drowsiness as a side effect than subjects in group 2 at 0.05 level of significance? Determine the null and alternative hypothesis? find the test statistic for this hypothesis test? determine the P value for this hypothesis test? do we reject or not reject the null hypothesis and why? State your conclusion?
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