A compound is known to have a free amino group with a pKa of 8.6, and one other ionizible group with a pKa between 5 and 7. To 90mL of a 0.150M solution of this compound at pH 7.80 was added 35 mL of a solution of 0.18 M HCl. The pH changed to 6.40. What is the pKa of the second ionizable group?
Neutral Amino Acids
Amino acids which do not have any charge on them are neutral amino acids.
Globular Protein
The globular proteins refer to the shape of protein specifically spherical in nature apart from spherical form fibrous, disordered and membrane-bound proteins exist. These globular proteins are miscible in water and form a colloidal solution rather than other types which might not exhibit solubility. Many classes of the fold are found in globular proteins, which render them a sphere shape. Globular fold containing proteins usually are referred to by the term globin.
Dimer
Dimers are basic organic compounds, which are derivates of oligomers. It is formed by the combination of two monomers which could potentially be strong or weak and in most cases covalent or intermolecular in nature. Identical monomers are called homodimer, the non-identical dimers are called heterodimer. The method by which dimers are formed is known as “dimerization”.
Dipeptide
A dipeptide is considered a mixture of two distinct amino acids. Since the amino acids are distinct, based on their composition, two dipeptide's isomers can be produced. Various dipeptides are biologically essential and are therefore crucial to industry.
A compound is known to have a free amino group with a pKa of 8.6, and one other ionizible group with a pKa between 5 and 7. To 90mL of a 0.150M solution of this compound at pH 7.80 was added 35 mL of a solution of 0.18 M HCl. The pH changed to 6.40. What is the pKa of the second ionizable group?
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