A double-strand break has activated ATM. Select all the statements that are true of the activated pathway. p53 must be phosphorylated. p21 inhibits the phosphorylation of Rb protein, which allows cell cycle arrest. PUMA inhibits Bcl-2, thereby allowing apoptosis. p53 must be released from Mdm2.

A double-strand break has activated ATM. Select all the statements that are true of the activated pathway. p53 must be phosphorylated. p21 inhibits the phosphorylation of Rb protein, which allows cell cycle arrest. PUMA inhibits Bcl-2, thereby allowing apoptosis. p53 must be released from Mdm2.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter17: Genes And The Immune System

Section: Chapter Questions

Problem 10QP: The Adaptive Immune Response Is a Specific Defense Against Infection Researchers have been having a...

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Question

A double-strand break has activated ATM. Select all the statements that are true of
the activated pathway.
p53 must be phosphorylated.
p21 inhibits the phosphorylation of Rb protein, which allows cell cycle arrest.
PUMA inhibits Bcl-2, thereby allowing apoptosis.
p53 must be released from Mdm2.

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