Which of the following must occur for programmed cell death (apoptosis): 1. p53 must be stabilized 2. M-Cdk must be active 3. Caspases must be inactivated 4. There must be local inflammation
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Which of the following must occur for programmed cell death (apoptosis):
Step by step
Solved in 3 steps
- Which of the following types of mutations would be most likely to cause cells to undergo apoptosis (programmed cell death)? One that increases the affinity of p21 for Cdks One that decreases the affinity of Rb for the transcription factor E2F One that decreases the ability of p53 to bind to DNA One that causes p53 to be constitutively phosphorylatedWhich of the following is an inhibitor of apoptosis? Question 3 options: a) Caspase b) cytochrome c c) Bcl-2 family d) p53Which of the following would most likely promote necrosis? Select one: a. activation of p53 b. activation of cdk c. pathogenic infection d. inactivation of p53 e. cyclin Clear my choice
- Which of the following could be classified as an oncogene? None are possible oncogenes A mutant of MAP kinase that was active with or without being phosphorylated All are possible oncogenes A mutant of MEK with significantly reduced enzyme activity A mutant cAMP phosphodiesterase that made it super-activeWhen p53 is activated, a cell cannot progress: A. throught M-phase B. from G2 into M phase C. From G1 into S phase D. Throught S-phase E. from s-pahse into G2Which of the following proteins would least likely promote arrest of cell division or apoptosis? Select one: a. p21 b. superoxide c. retinoblastoma d. p53 e. cyclin
- Which protein is a positive regulator that phosphorylates other proteins when activated? a. p53 b. retinoblastoma protein (Rb) c. cyclin d. cyclin-dependent kinase (Cdk)Which of the following statements correctly describes p53? Which of the following statements correctly describes p53? A) It is a membrane receptor that binds to growth factors such as EGF. B) p53 binds to pre-replication complexes promoting the transition from G1 to S phase. C) p53 activates cyclin-CDK complexes. D) Activation of p53 leads to inhibition of the cyclin-CDK complexes. E) Cell division stops until p53 binds to DNA and repairs the damage.Which of the following statements is true? Question 9 options: a) Executioner caspases are activated by cleavage. b) Initiator caspases are activated by cleavage. c) Executioner caspases are activated by dimerization. d) Executioner caspases trigger apoptosis but initiator caspases does not.
- In a healthy cell, which of the following proteins will be activated in order to suppress cell division if the cell is not ready or should not divide? Select one: a. p53 b. cdk c. cyclin d. seperase e. mitogenThe Adaptive Immune Response Is a Specific Defense Against Infection In cystic fibrosis gene therapy, scientists propose the use of viral vectors to deliver normal genes to cells in the lungs. What immunological risks are involved in this procedure?Define the following terms: a. cell transformation b. oncogene c. apoptosis d. early response gene e. delayed response gene
