A hypothetical population has two alleles for an "T" gene: T and t. In a random sample of 50 diploid zygotes (for a total of What is the frequency of the homozygous recessive genotype? alleles), the following genotypes were found: 15 TT, 25 Tt, and 10 tt. O A. 0.45 O B. 0.20 O C.0.50 O D.0.55
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- a) Suppose the frequency of the recessive allele a for the recessive condition albinism is 0.2 Assume the Hardy-Weinberg distribution. ai) What is the frequency of albinism in the general population? aii) What fraction of the population are carriers? b) In a large population of mice, 0.58 have the recessive genetic condition rsiancer (fictional). Assume the Hardy-Weinberg distribution. What fraction of mice are carriers? Giver your answer with two digits parts the decimal point. c) In a large population of squirrels, 0.14 have the recessive genetic condition nlourianfilindr (fictional). Assume the Hardy-Weinberg distribution. What is the frequency of the dominant allele in this population? Give your answer with two digits parts the decimal point. d) In a large population of chimpanzees, there is a recessive genetic condition telactalase (fictional). Assume the Hardy-Weinberg distribution. If the frequency of dominant allele is 0.77 then what fraction of the population has…a) The allele frequency of albinism is 0.12 in a population of 450 individuals. If the number of individuals that are carriers of albinism is 101. Calculate the number of individuals with normal pigmentation? b) A rare disease which is due to a recessive allele (A) that is lethal when homozygous occurs within a specific population at a frequency of three in a million. How many individuals in a town with a population of 3000 will be expected to carry this allele?Nieman-Pick Syndrome involves a defective enzyme, sphyngomylinase. It is usually fatal before the age of 3. The defective allele frequency is 0.01 in Ashkenazi populations. Let’s call the healthy allele A, and the lethal allele a. a) What is the frequency of allele A? Assuming Hardy-Weinberg equilibrium, how many people do you expect to have the three genotypes in a population of 10,000? b) AA:_______ c) Aa:________ d) aa:_________
- 60 individuals have the genotype AA28 individuals have the genotype Aa12 individuals have the genotype aaWhat is the frequency of the A allele?Think of how many alleles in total?hint: add up the number of A alleles in this population: AA= 60+60 and Aa= 28.Add those together and divide by the total number of alleles.A mouse mutation with incomplete dominance (t =tailless) causes short tails in heterozygotes (t+/t). Thesame mutation acts as a recessive lethal that causeshomozygotes (t/t) to die in utero. In a populationconsisting of 150 mice, 60 are t+/t+ and 90 areheterozygotes.a. What are the allele frequencies in this population?b. Given that there is random mating among mice, nomigration, and no mutation, and ignoring the effects of random genetic drift, what are the expectednumbers of the different genotypes in this nextgeneration if 200 offspring are born?c. Two populations (called Pop 1 and Pop 2) of micecome into contact and interbreed randomly. Thesepopulations initially are composed of the followingnumbers of wild-type (t+/t+) homozygotes andtailless (t+/t) heterozygotes:Pop 1 Pop 2Wild type 16 48Tailless 48 36What are the frequencies of the two genotypes in thenext generation?A group of four birds flies to a new location and starts a newcolony. Three of the birds are homozygous AA, and one bird isheterozygous Aa.A. What is the probability that the a allele will become fixed in thepopulation via genetic drift?B. If fixation of the a allele occurs, how long will it take?C. How will the growth of the population, from generation togeneration, affect the answers to parts A and B? Explain.
- Which of the following statements describes an example of genetic drift?a. Allele g for fat production increases in a small population because birds with more bodyfat have higher survivorship in a harsh winter.b. Random mutation increases the frequency of allele A in one population but not inanother.c. Allele R reaches a frequency of 1.0 because individuals with genotype rr are sterile.d. Allele m is lost when a virus kills all but a few individuals and just by chance, none ofthe survivors possess allele m.Assuming a population is in Hardy-Weinberg equilibrium, an increase in the frequency of the p(A) allele from 0.6 to 0.9 would result in which of the following outcomes? a. A decrease in the number of homozygous dominant individuals within the population b. A decrease in the number of homozygous recessive individuals within the population c. An increase in the number of homozygous recessive individuals within the population d. An increase in the number of heterozygotes within the population e. No change in genotypic frequency within the populationFrom the same population of dragons. Two alleles B and encoding for phenotypes blue and purple scales, P is dominant over B. You have a population of 345 individuals. PP = 100; BP = 90 , and BB = 145 . What is the frequency of the B allele? Please use and round to four decimal points.
- In achondroplastic dwarfism, an autosomal dominant disease, the gene is lethal in homozygotes. If the frequency of the normal allele is 0.99, what is the heterozygote frequency? a. 0.01 b. 0.02 c. 0.98 d. 0.99 An autosomal recessive gene is lethal in homozygotes. In a population at Hardy- Weinberg equilibrium, how many generations will it take to eliminate the gene from the population a.100 b.It will not be eliminated from the population. c.1 d.25A researcher examines a locus, or marker, in which there is a particular C/T polymorphism in a population of interest. Let’s call this Locus 1. They obtain the following genotype counts in a sample of the population: CC:42, CT:16, TT:32. a) Calculate the genotype frequencies and the allele frequencies for Locus 1 in the sample.b) Calculate the observed heterozygosity (the frequency of heterozygotes) and the observed homozygosity (the total frequency of all homozygotes) in the sample. Ensure that these two frequencies add up to 1.In a Hardy-Weinberg population with two alleles, G and g, that are in equilibrium, 40% of the alleles are recessive. What percentage of the population is homozygous for the dominant allele? a. 9% b. 36% c. 70% d. 60% e. 30%