A sudden, novel genetic change which can be stably inherited (as in the case of red flower color appearing suddenly in the normal yellow-flowering evening primrose) is the accepted definition of: DNA damage (as proposed by Hugo de Vries) non-homologous recombination (as proposed by Hugo de Vries) transposition (as proposed by Hugo de Vries) homologous recombination (as proposed by Hugo de Vries) mutation (as proposed by Hugo de Vries)

A sudden, novel genetic change which can be stably inherited (as in the case of red flower color appearing suddenly in the normal yellow-flowering evening primrose) is the accepted definition of: DNA damage (as proposed by Hugo de Vries) non-homologous recombination (as proposed by Hugo de Vries) transposition (as proposed by Hugo de Vries) homologous recombination (as proposed by Hugo de Vries) mutation (as proposed by Hugo de Vries)

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter16: Human Genetics And The Human Genome

Section: Chapter Questions

Problem 12TYU: SCIENCE, TECHNOLOGY, AND SOCIETY Imagine that you are a genetic counselor. What advice or...

See similar textbooks

Similar questions

SCIENCE, TECHNOLOGY, AND SOCIETY Imagine that you are a genetic counselor. What advice or suggestions might you give in the following situations? (a) A couple has come for advice because the woman had a sister who died of Tay-Sachs disease. (b) A young man and woman who are not related are engaged to be married. However, they have learned that the mans parents are first cousins, and they are worried about the possibility of increased risk of genetic defects in their own children. (c) A young womans paternal uncle (her fathers brother) has hemophilia A. Her father is free of the disease, and there has never been a case of hemophilia A in her mothers family. Should she be concerned about the possibility of hemophilia A in her own children? (d) A 20-year-old man is seeking counseling because his father was recently diagnosed with Huntingtons disease. (e) A 45-year-old woman has just been diagnosed with Huntingtons disease. She says she will not tell her college-age sons because of the burden it will place on them. Given that the woman, not her sons, is your client, do you have a duty to inform the sons? Explain your reasoning.
You graduate and land a job in a medical genetics laboratory. A particular family has been identified in which a heritable genetic disease has arisen. Through genetic mapping, you identify a mutation in afflicted individuals that is likely causing this condition. In unafflicted members of this family, a region in the coding sequence of the gene in question has the sequence: 5’-CACATGATGATGATGATGATGCGT-3’ However in afflicted individuals, the gene has the sequence: 5’-CACATGATGATGATGATGATGATGATGCGT-3’. (A) Please propose a detailed mechanism for how this genetic change could have arisen, and illustrate this with a diagram below or on the back of this page. (B) Would mutations affecting this region of the gene be likely to cause a frame-shift in the protein coding sequence? Why or why not? In a related genetic disease, the wild-type or normal allele has the sequence: 5’-CAGCACACACACACACACACAGGTG-3’ (C) Would mutants arising via the mechanism you just described be likely to result…
Being able to understand the relationship between DNA, mRNA, tRNA, ribosomes and proteins, is necessary for any researcher interested in gene therapy. Gene therapy is dedicated to correcting genetic defects by replacing mutated genes with wildtype versions. This can include complete removal and introduction of a working copy of the entire gene (using knock-outs and knock-ins) or removal of only the actual mutated nucleotide. Sickle Cell Disease is an example of a recessive disorder based on a single-point mutation: GAG becomes GTG, which encodes a new amino acid. One would only need to replace a single base to correct the disorder making it very attractive to gene therapy researchers. The mutant sickle cell allele is called HbS (for sickled hemoglobin) while the wt allele is HbA. Pretend that Arcel Kasongo, a masters student from Cambridge, is studying for an oral exam on gene therapy, and has an especial interest in the disorder since he comes from the Democratic Republic of Congo…
Being able to understand the relationship between DNA, mRNA, tRNA, ribosomes and proteins, is necessary for any researcher interested in gene therapy. Gene therapy is dedicated to correcting genetic defects by replacing mutated genes with wildtype versions. This can include complete removal and introduction of a working copy of the entire gene (using knock-outs and knock-ins) or removal of only the actual mutated nucleotide. Sickle Cell Disease is an example of a recessive disorder based on a single-point mutation: GAG becomes GTG, which encodes a new amino acid. One would only need to replace a single base to correct the disorder making it very attractive to gene therapy researchers. The mutant sickle cell allele is called HbS (for sickled hemoglobin) while the wt allele is HbA. Pretend that Arcel Kasongo, a masters student from Cambridge, is studying for an oral exam on gene therapy, and has an especial interest in the disorder since he comes from the Democratic Republic of Congo…
Which of the following is an example of a balanced mutation? Group of answer choices inversions deletions aneuploidy tandem duplications
The coloration of calico cats is also the result of the inactivation of one of a female cat's sex chromosomes. In females, two X chromosomes are present in all cells but only one is active, the inactive one is called a BARR BODY. This is why the coat color is random, even among cloned calico cats that have identical genomes. Calico is a coat color found in cats, which is caused by a SEX-LINKED, CODOMINANT allele.
Which of the following process generates a new copy of the transposable element at a new location of DNA?a) Homologous genetic recombinationb) Site specific recombinationc) Non-homologous recombinationd) Replicative recombination
Which of the following statements is true regarding gene duplication? (Check all that apply) extra gene copies are highly deleterious duplications arise through unequal crossing over duplicates in the same gene family are called paralogs duplication is an important source of new genes duplications confound the pairing of homologous chromosomes, leading to fertility problems
1. The first genetic test developed for this disease took advantage of a large family of over 2,000 individuals who lived along Lake Maracaibo in Venezuela. These family members, some with and some without Huntington’s disease, could all trace their ancestry to a single female who settled in the region a number of generations ago.Genomic DNA from family members with and without Huntington’s disease was cut with a set of enzymes that make reproducible cuts at known DNA sequences. These DNA fragments were run on a DNA gel to see which fragments correlated with the presence of Huntington’s disease. a) How might the large number (over 2,000) of family members who have a common ancestor who suffered from Huntington’s disease make it easy to narrow down the gene location of the Huntington’s locus (compared to doing the same experiment with a small family descended from a Huntington’s sufferer)?
A haplotype is a set of DNA variations, or polymorphisms, that tend to be inherited together. A haplotype can refer to a combination of alleles or to a set of single nucleotide polymorphisms (SNPs) found on the same chromosome. Each SNP represents a difference in a single nucleotide. For example, an SNP may replace the cytosine (C) with thymine (T) in a certain stretch of DNA. SNPs occur normally throughout a person’s DNA. They occur almost once in every 1,000 nucleotides on average, which means there are roughly 4 to 5 million SNPs in a person's genome. These variations may be unique or occur in many individuals; Most commonly, these variations are found in the DNA between genes. They can act as biological markers, helping scientists locate genes that are associated with disease. When SNPs occur within a gene or in a regulatory region near a gene, they may play a more direct role in disease by affecting the gene’s function. Nucleotide Position…
Give a schematic diagram of how we can Treatment Down Syndrome by using gene therapy? Please answer at your own words,please..
Give a schematic diagram of how we can Treatment Down's syndrome by using gene therapy? Please answer at your own words,please..