6..a) The structure of penicillin G is shown below. Circle the most acidic proton in the structure and give anapproximate pKa value for that proton in the box povided.ortxPenicillin G +b) Based on your answer to part (a), calculate the equilibrium constant for the reaction of penicillinG with ammonia. Be sure to show your work for partial credit!NH3Penicillin GPenicillin GO₂NApproximate pka =0pka =SHNH4Keqc) The pka value of protonated penicillin G is approximately 6. Based on this information, calculate thepKa value ofthe thiol shown below, given that the equilibrium constant for the reaction is approximately 1.OH= 1O₂N+DeprotonatedPenicillin GKea=ProtonatedPenicillin GpK₂ = 6

Answered: Image /qna-images/answer/03667a96-97ae-438a-9581-77ce1122c35d.jpg

a) The structure of penicillin G is shown below. Circle the most acidic proton in the structure and give an approximate pKą value for that proton in the box povided. Penicillin G + NH3 Penicillin G H orty b) Based on your answer to part (a), calculate the equilibrium constant for the reaction of penicillin G with ammonia. Be sure to show your work for partial credit! Penicillin G pK₂ = Approximate pK₂ = SH NH4 Keq = 1 OH c) The pką value of protonated penicillin G is approximately 6. Based on this information, calculate the RK value ofthe thiol shown below, given that the equilibrium constant for the reaction is approximately O₂N + Deprotonated Penicillin G Kea = + Protonated Penicillin G pK₂ = 6

a) The structure of penicillin G is shown below. Circle the most acidic proton in the structure and give an approximate pKą value for that proton in the box povided. Penicillin G + NH3 Penicillin G H orty b) Based on your answer to part (a), calculate the equilibrium constant for the reaction of penicillin G with ammonia. Be sure to show your work for partial credit! Penicillin G pK₂ = Approximate pK₂ = SH NH4 Keq = 1 OH c) The pką value of protonated penicillin G is approximately 6. Based on this information, calculate the RK value ofthe thiol shown below, given that the equilibrium constant for the reaction is approximately O₂N + Deprotonated Penicillin G Kea = + Protonated Penicillin G pK₂ = 6

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter9: Addition Via Cyclic Intermediate

Section: Chapter Questions

Problem 2E

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