A vaccination is developed for a novel viral infection, and the antigen used corresponds to a short stretch of a protein found on the surface of the virus. In clinical trials, people who were exposed to the virus a second time had superior immunity to people who were given the vaccine then exposed to the virus for the first time. What is the BEST explanation for this difference? The vaccination promoted the production of all memory B cells whereas natural infection promoted the proliferation of only those memory B cells specific to the virus. The vaccination promoted the production of the correct memory B cells whereas natural infection did not. People exposed to the virus were able to make many different antibodies that bind different antigens on the virus. Vaccinations promote selection of memory B cells, whereas a natural infection triggers production of cytotoxic B cells.

A vaccination is developed for a novel viral infection, and the antigen used corresponds to a short stretch of a protein found on the surface of the virus. In clinical trials, people who were exposed to the virus a second time had superior immunity to people who were given the vaccine then exposed to the virus for the first time. What is the BEST explanation for this difference? The vaccination promoted the production of all memory B cells whereas natural infection promoted the proliferation of only those memory B cells specific to the virus. The vaccination promoted the production of the correct memory B cells whereas natural infection did not. People exposed to the virus were able to make many different antibodies that bind different antigens on the virus. Vaccinations promote selection of memory B cells, whereas a natural infection triggers production of cytotoxic B cells.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter19: Population Genetics And Human Evolution

Section: Chapter Questions

Problem 1CS: If you suspected that heterozygous carriers of a particular disease gene had a selective advantage...

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Edward Jenner, in eighteenth-century England, first inject-ed a child with a totally untested smallpox vaccine and then,after a time, injected that child with living smallpox virus. Whatwould be the likely reaction to someone performing a similarexperiment today? How do you think a scientist of today wouldtest a potential new vaccine?
If you suspected that heterozygous carriers of a particular disease gene had a selective advantage in resisting a type of infection, how would you go about testing that hypothesis?
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