Succinyl-CoA Synthetase mechanismSuccinyl-CoA synthetaseenzyme active siteO Substrates bindto the active siteCOOof succinyl-CoAsynthetaseCH2OHHisCH2. Succinyl-CoACOA-GuanosinePhosphoryl grouptransfer to GDP toform GTP, which isreleased from the2 Formation ofsuccinyl-phosphateCOAGTPenzymeFormation ofphosphohistidineGuanosineCOOPhosphohistidineCH2GDPGDPCH2COOCH2| "SuccinateCH,Succinyl-phosphateČOOa) Which catalytic mechanism occurs in step 2?b) Why must phosphate first bind to succinyl-CoA before interacting with the His site and GDP?

Glycolysis, TCA cycle, and ETC all are interconnected processes. Respiration is an oxidative…

Answered: a) Which catalytic mechanism occurs in…

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 14P

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a) Which catalytic mechanism occurs in step 2? b) Why must phosphate first bind to succinyl-CoA before interacting with the His site and GDP?