Q: Define origin-recognition complex (ORC)
A: The field of biology that studies the composition, and structure of the molecules and also the…
Q: what are the purpose of sequence alignment? define local alignment and global alignment?
A: Alignments are an effective method for comparing similar DNA or protein sequences. DNA molecules are…
Q: Describe the strange nature of highly repetitive sequences and their function.
A: Introduction : Mammalian genomes have two major types of highly repetitive sequences: interspersed…
Q: List the different features of coding?
A: The set of different rules that are used through the living cells for translating information that…
Q: Describe the composition of a DNA microarray, and explain how it is used.
A: A DNA microarray is a laboratory tool which is used to detect the expression of thousands of genes…
Q: Define repetitive sequence, and explain how repetitive sequences affect genome sizes.
A: All the genetic material that an organism has is referred as genome. The genetic material can be in…
Q: describe insertion sequences
A: DNA is the information centre for most organisms. DNA is made up of a long chain of nucleotide base…
Q: Discuss the significance of protein sequencing.
A: Protein sequencing is a process of determining the sequence of amino acids of a protein.
Q: suggest reasons for why DNA mutations are not all phenotypic.
A: Mutation is a change in nucleotide sequence of DNA which can occur either due to mistakes during DNA…
Q: Explain Deletion-insertion polymorphisms (DIPs)?
A: DIPs or Deletion-Insertion polymorphisms is defined as a large number of consistent genetic variants…
Q: Explain the basic techniques used to manipulate genetic material
A: Genetic Material: A cell or an organism comprises information carrier materials found in the…
Q: Defi ne palindrome and draw three different palindromic sequences.
A: DNA( deoxyribonucleic acid) is the double-stranded molecule that is the genetic material in most…
Q: outline HOW to clone and identify a new gene!
A: Gene clonning is technique of genetic engineering where a gene of intrest is isolated from its DNA…
Q: Compare proof reading and repair .
A: There can be error during the replication of DNA which is corrected by proof reading and repair of…
Q: Discuss the differences between the study of genomicsand proteomics.
A: Study of genes and it's behavior is known as genomics
Q: Explain the central dogma of genetics at the molecular level.
A: In literal sense, dogma refers to a definite set of principles or processes. Central dogma refers to…
Q: State and describe the benefits of using whole-genome sequencing for diagnosis.
A: The whole genome shotgun method involves cloning, followed by accurate computer sequencing of the…
Q: Why a multiple sequence alignment is needed for researchers? What inferences can be derived from…
A: When three or more biological sequences are aligned and studied together, it is referred to as…
Q: Explain why accuracy is more important for DNA replication than for transcription
A: DNA replication is that the method by that a double-stranded DNA molecule is traced to provide 2…
Q: Identify (circle the mutation in the mutated sequence) and name the type of mutation that occurred.
A: # Here I have given solution of mutations only , please send next question related to genetics…
Q: Explain the mechanisms on the proofreading of DNA.
A: Biological macromolecules are those large molecules that are necessary for the survival and growth…
Q: What does 'biological sequence database' refer to?
A: Bioinformatics aids in the storage and process of large biological information by the aid of…
Q: describe the main steps required to clone a gene and produce a protein.
A: Gene cloning is the technique of locating and copying (cloning) a gene of interest from all the DNA…
Q: explain the similarities and differences between the methods used in transcriptomics and genomics
A: Genomics is the study of genomes through analysis, sequencing and mapping of genes and…
Q: process of overlap assembly in whole genome sequencing
A: Genome sequencing Genome sequencing or gene sequencing is a way of arranging nucleotides the n the…
Q: Define about RNA sequencing (RNA-seq) ?
A: The RNA in a cell contains information that is used to make proteins and perform other important…
Q: Draw the structure of a typical insertion sequence and identify its parts.
A: There are two types of transposons such as replicative and non-replicative transposons. They are…
Q: Outline different strategies for identifying gene sequences.
A: Genome is the study of all genes present in the organism. Gene is a unit of heredity that is…
Q: What is Intron retention type of alternativesplicing ?
A: A portion in mRNA that codes for protein is termed as exon. The non-coding region is termed as…
Q: Explain how substitution matrices can be used to improve the possibility of identifying related…
A: Protein is a macronutrient that is vital for building muscle mass. It is normally found in creature…
Q: What are the factor of expressed sequence tag?
A: Expressed sequence tags are small stretches of DNA sequences that are typically 100 to 800…
Q: Genetic engineering and gene therapy are similar fields within genomics. What do they have in common…
A: Genetic engineering and gene therapy are similar fields with genomics. They are both similar as they…
Q: Explain the importance of Proteomics ?
A: The extensive study of proteomes is known as proteomics. An organism, system, or biological setting…
Q: describe Deletion-insertion polymorphisms (DIPs)
A: Polymorphism: Many forms of a allele is termed as polymorphism. The polymorphism leads to the…
Q: Explain how protein-encoding regions are found when analyzing a DNA sequence.
A: Genes and intergenic gaps are found in the DNA of eukaryotes. Exons and introns are the two subunits…
Q: a- What is genome assembly?
A: Sequence assembly is the process of matching & combining segments from a larger DNA sequence in…
Q: Explain the types of sequencing techniques
A: DNA sequencing techniques are methods used for the identification of order or sequence of…
Q: Explain the fundamental challenges of genomics ?
A: Genomics is the branch of biotechnology that deals with the structure, function, evolution and…
Q: Discuss why it is useful to search a database to identify sequencesthat are homologous to a newly…
A: The most basic operations in bioinformatics involves searching for similarities, or homologies,…
Q: Describe the process for shotgun sequencing of a genome. Practice aligning the two sets of sequenced…
A: Two questions have been asked. first question has been answered. To get the answer for your second…
Q: Describe how lon torren method of sequencing works in detail.
A: Thermo Fisher Scientific's Ion Torrent technology introduces a completely new approach to Next…
Q: Explain the use of Annotation to Identify Gene Sequences ?
A: The attachment of biological information to the gene sequence is known as genome annotations. Three…
Q: Describe how Ion torren method of sequencing works in detail.
A: Thermo Fisher Scientific's Ion Torrent technology brings a whole new method to Next Generation…
Q: Explain the Encoding Genetic Information.
A: Encoding refers to the conversion of one form into another and biological encoding refers to the…
Q: compare oligonucleotide arrays and expression arrays
A: An oligonucleotide array is made up of a collection of short single-stranded DNA sequences…
Q: Describe several methods commonly used for the sequencing of DNA
A: DNA sequencing refers to the sequencing of the nucleotides base pairs in the genome of an organism.…
Q: What is the E-value of the sequence, what does your E-value reflect and what’s the importance of an…
A: Bioinformatics is the branch of science that deals with the genome, gene, and protein sequences. It…
Q: Describe two different types of protein microarrays, and discuss their uses.
A: Genomics and proteomics are relatively new branches of genetics. Genomics is the study of all the…
Q: Explain the process of determining the Gene Sequence ?
A: DNA sequencing can be outlined as the phenomenon which is used for determining the sequence of the…
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- Why a multiple sequence alignment is needed for researchers? What inferences can be derived from this kind of sequence alignments? Explain two extreme cases that are non-informative for the multiple sequence alignment.What are the similarities and/or differences between interpreting Multiple Sequence Alignment (MSA) of conserved sequences at the DNA level versus the Amino Acid level? Please site references if possible and have 5+ sentences.What is meant by the term "alignment" in genomic research and in what ways does alignment aid sequence assembly? How can relying on alignment lead to potential errors?
- How are the gap penalties adjusted in the ClustalW multiple sequence alignment program to improve the algorithm? Indicate the logic only.If you have access to the necessary computer software, make asequence file and analyze it in the following ways: What is thetranslated sequence in all three reading frames? What is the longest open reading frame? Is the sequence homologous to any known sequences? If so, does this provide any clues about the function of the sequence?what is the whole-genome shotgun sequencing? Also briefly explain its strategy to assemble the genome sequence.
- Why are closure and completeness important in genome sequencing?You wish to align a 300 bp nucleotide sequence to a genome. Which of the following pairwise sequence alignment algorithms is BEST suited for this task? Global alignment or Local alignment? Please explain or elaborate why you chose this alignment algorithm.What does BLAST stand for? Basic Local Alignment Search Tool Basic Local Alignment SequenceTool Best Local Alignment Search Tool Best Local Algorithm Search Tool