Question one parts A though ea. You have a plan to make the cellular signaling peptide RGD (Arg-Gly-Asp). If you are beginning fromthe Arginine (Arg) amino acid, which amino acid(s) will require NH2 protection to optimize thesynthesis?A) All 3 amino acids will need NH2 protectionB) Gly and Asp will need NH2 protectionC) Arg and Gly will need NH2 protectionD) Only Argb. Which of the following amino acids will not produce a purple color (indicative of 2 ninhydrinmolecules binding) when reacted with ninhydrin?A) phenylalanineB) valineC) prolineD) histidinec. If you had a mixture of leucine, arginine, and glutamic acid in a pH of 6 and applied a drop onto paperconnected to an electrophoresis apparatus. Which of these would move toward the cathode (-).A) LeucineB) ArginineC) Glutamic AcidD) None of themd. True/False - Dicyclehexvlcarbodiimide is a typical reagent in peptide synthesis for protectingcarboxylic acid groups.e. True/False t-butoxycarbonyl dicarbonate (Boc20) adds a t-butoxy carbonyl group to the amineportion of the amino acid creating an amide (carbamate) and protects the amine portion from sidereactions.

Answered: Image /qna-images/answer/94e192a6-82b6-4063-9620-b7f87ae34a9b.jpg

a. You have a plan to make the cellular signaling peptide RGD (Arg-Gly-Asp). If you are beginning from the Arginine (Arg) amino acid, which amino acid(s) will require NH2 protection to optimize the synthesis? A) All 3 amino acids will need NH2 protection B) Gly and Asp will need NH2 protection C) Arg and Gly will need NH2 protection D) Only Arg b. Which of the following amino acids will not produce a purple color (indicative of 2 ninhydrin molecules binding) when reacted with ninhydrin? A) phenylalanine B) valine C) proline D) histidine c. f you had a mixture of leucine, arginine, and glutamic acid in a pH of 6 and applied a drop onto paper connected to an electrophoresis apparatus. Which of these would move toward the cathode (-). A) Leucine B) Arginine C) Glutamic Acid D) None of them d. True/False - Dicyclohexylcarbodiimide is a typical reagent in peptide synthesis for protecting carboxylic acid groups. e. True/False t-butoxycarbonyl dicarbonate (Boc20) adds a t-butoxy carbonyl group to the amine portion of the amino acid creating an amide (carbamate) and protects the amine portion from side reactions.

a. You have a plan to make the cellular signaling peptide RGD (Arg-Gly-Asp). If you are beginning from the Arginine (Arg) amino acid, which amino acid(s) will require NH2 protection to optimize the synthesis? A) All 3 amino acids will need NH2 protection B) Gly and Asp will need NH2 protection C) Arg and Gly will need NH2 protection D) Only Arg b. Which of the following amino acids will not produce a purple color (indicative of 2 ninhydrin molecules binding) when reacted with ninhydrin? A) phenylalanine B) valine C) proline D) histidine c. f you had a mixture of leucine, arginine, and glutamic acid in a pH of 6 and applied a drop onto paper connected to an electrophoresis apparatus. Which of these would move toward the cathode (-). A) Leucine B) Arginine C) Glutamic Acid D) None of them d. True/False - Dicyclohexylcarbodiimide is a typical reagent in peptide synthesis for protecting carboxylic acid groups. e. True/False t-butoxycarbonyl dicarbonate (Boc20) adds a t-butoxy carbonyl group to the amine portion of the amino acid creating an amide (carbamate) and protects the amine portion from side reactions.

Biochemistry

9th Edition

ISBN:9781305961135

Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal

Publisher:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal

Chapter3: Amino Acids And Peptides

Section: Chapter Questions

Problem 54RE: THOUGHT QUESTION Imagine we identify a gene that is directly responsible for the effects of...

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