According to Research and Development department analysis results, it was concluded that a two-stage control strategy was optimal for antibody production. In the first stage, conditions were optimized for cell growth. In the second stage, conditions were changed to halt cell growth. Please answer the following questions in 1-2 sentences. (a) Why did they choose this two-stage approach?  (b) How did they cause the cells to shift from a growth phase to a quiescent (non-growth) phase?  (c)Please discuss which factors influence the choice of bioreactor design for optimal antibody production  (Hint: The production of antibody which is anchorage-dependent systems from continuous cell lines can be accomplished using several bioreactor configurations, each of which was designed to satisfy differing operational, product quality, economic, and production scale requirements

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A:

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