Adipose tissue cannot resynthesize triacylglycerols from glycerol released during lipolysis (fat breakdown). Why not? Describe the metabolic route that is used to generate a glycerol compound for triacylglycerol synthesis.
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Adipose tissue cannot resynthesize triacylglycerols from glycerol released during lipolysis (fat breakdown). Why not? Describe the
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- Triacylglycerols in adipose tissue do not enter the bloodstream as triacyglycerolsexplainWhat impact would an increase in intramitochondrial oxaloacetate have on fatty acid synthesis? Justify your response succinctly.The removal of fatty acids from triacylglycerols leaves glycerol. Show how the actions of glycerol kinase and glycerol-3-phosphatedehydrogenase on glycerol produce an intermediate of glycolysis.
- Explain why adipocytes need glucose as well as fatty acids in order to synthesize triacylglycerols.Which of the following enzyme components of fatty acid synthase has/have a thiol group? A. ketoacyl-ACP reductase B. ketoacyl-ACP synthase C. enoyl- ACP reductase D. acyl carrier proteinFatty acids are stored in adipose tissue, as triacylglycerol (TAG) forms. TAGs are degraded as glycerol and fatty acids where energy is required. Based on that knowledge explain: How these products are used in the adipose, liver, and other tissue? Why glycerol can not be metabolized in adipose tissue?
- The removal of fatty acids from triacylglycerols leaves glycerol. Show how the actions of glycerol kinase and glycerol-3-phosphate dehydrogenase on glycerol produce an intermediate of glycolysis.The pentose phosphate pathway is quite active in adipose tissue. Why? Explain how this pathway complements lipogenesis with the use of an example (such as a person eating chocolate).Thioester play an important role in glycolysis and the TCA cycle. Which reactions in glycolysis and tca cycle involve thioesters.
- Briefly explain why chicken fat, which largely consists of various triacylglycerols, has such a higher energy content per mole compared to sucrose.Fatty acids from stored triacylglycerols (fat) are not available for gluconeogenesis. Speculate why we do not have the enzymes to directly convert fatty acids into glucose. Plants (especially seeds) do have enzymes to convert fatty acids into carbohydrates. Why are they so lucky?Glycerol generated from TG hydrolysis in adipocytes is converted by the liver into _____________, which serves as a substrate for the synthesis of glucose.