"Agent V" is the name of an anticancer (chemotherapy) drug. This drug works against cancer cells by inhibiting the formation of microtubules in sensitive cells. Consider a cell that is sensitive to agent V (in other words, agent V is effective at stopping growth of this cell). Based on this information, agent V would cause the cell to be frozen at which of the major cell cycle checkpoints (G1, G2 or M checkpoint)? Explain your answer in 2- 4 sentences.

"Agent V" is the name of an anticancer (chemotherapy) drug. This drug works against cancer cells by inhibiting the formation of microtubules in sensitive cells. Consider a cell that is sensitive to agent V (in other words, agent V is effective at stopping growth of this cell). Based on this information, agent V would cause the cell to be frozen at which of the major cell cycle checkpoints (G1, G2 or M checkpoint)? Explain your answer in 2- 4 sentences.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter2: Cells And Cell Division

Section: Chapter Questions

Problem 12QP: Why is cell furrowing important in cell division? If cytokinesis did not occur, what would be the...

See similar textbooks

Similar questions

"Agent V" is the name of an anticancer (chemotherapy) drug. This drug works against cancer cells by inhibiting the formation of microtubules in sensitive cells. Consider a cell that is sensitive to agent V (in other words, agent V is effective at stopping growth of this cell). Based on this information, agent V would cause the cell to be frozen at which of the major cell cycle checkpoints (G1, G2 or M checkpoint)? Explain
Which of the three cell cycle checkpoints represents the most important commitment for the cell to divide?
BPA is a chemical compound that has historically been used in themanufacture of plastic products. However, cells often mistake BPAcompounds for hormones that accelerate the cell cycle. Because ofthis, BPA is associated with an increased risk of certain cancers. Question: How might BPA interact with the cell cycle and its checkpoints?
Leland Hartwell, the third recipient of the 2001 NobelPrize in Physiology or Medicine, was acknowledged forhis characterization of cell cycle checkpoint pathways in the budding yeast S. cerevisiae. What is a cell cycle check-point pathway? When during the cell cycle do checkpoint
If the S cyclin is mutated at its phosphorylation site, which checkpoint will be affected? Which conditions will escape from control during the cell cycle?
BPA is a chemical compound that has historically been used in themanufacture of plastic products. However, cells often mistake BPAcompounds for hormones that accelerate the cell cycle. Because ofthis, BPA is associated with an increased risk of certain cancers. Question: Why do you think that very small concentrations of BPA mighthave a large effect on the cell?
How does the dysregulation of cell cycle checkpoints contribute to the development of cancer?
BPA is a chemical compound that has historically been used in the manufacture of plastic products. However, cells often mistake BPA molecules for hormones that accelerate the cell cycle. Because of this, BPA is associated with an increased risk of certain cancers.a. How might BPA interact with the cell cycle and its checkpoints?b. Why do you think that very small concentrations of BPA might have a large effect on a cell?
If the M checkpoint is not cleared, what stage of mitosis will be blocked? a. prophase b. prometaphase c. metaphase d. anaphase
The “Hayflick limit” is the number of times cells growing in tissue culture will divide before cell proliferation ceases. What experimental procedure can be employed to remove this limit?
In the experiment below, you have treated cells with different cancer drugs, stained them with propidium iodide, and analyzed them by flow cytometry. Which of the following histograms illustrates what you would expect to see in the event that the spindle assembly checkpoint is activated (focus on the solid line, the dotted line is normal cell cycle control)? 1. D 2. C 3. A 4.B
Shown here are two HeLa cancer cells that are just completing cytokinesis. Explain how the cell division of cancer cellslike these is misregulated. Identify genetic and other changesthat might have caused these cells to escape normal cell cycleregulation