an excitatory synapse and inhibitory synapse generate postsynaptic potentials on the same neuron what can happen? a. The generated potentials will sum up to make a larger postsynaptic potential. b. Nothing will happen, because inhibitory neurons will not form synapses on the same neurons as excitatory neurons. c. The postsynaptic potential generated by the inhibitory synapse will shunt the excitatory synapse, leading to a reduction in the postsynaptic potential. d. None of the above
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- Assume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and presynaptic excitatory neuron B terminates on the same postsynaptic cell on a dendrite located on the side of the cell body opposite the axon hillock. Explain why rapid firing of presynaptic neuron A could bring the postsynaptic neuron to threshold through temporal summation, thus initiating an action potential, whereas firing of presynaptic neuron B at the same frequency and the same magnitude of EPSPs may not bring the postsynaptic neuron to threshold.a.Would an action potential travels faster in an axon with a wide diameter or a small diameter? b. Would an action potential travel faster in an axon that is myelinated or unmyelinated?Suppose you want to cause the presynaptic terminal of an axon to release its transmitter. How could you do so without an action potential?A. Decrease the temperature at the synapse.B. Use an electrode to produce IPSPs in the postsynaptic neuron.C. Inject water into the presynaptic terminal.D. Inject calcium into the presynaptic terminal.
- Which one of these is an example of an excitatory postynaptic potential in a typical neuron? a) A voltage change from -70mV to -70.5mV b) A voltage change from +35mV to 0MV c) A voltage change from 0mV to +0.35mV d) A voltage change from -69.5mV to -70mVdiscuss the process of the neuron firing an action potential from the resting period to the refractory period? Give an example of this in a different scenario.What membrane protein of the neuron is responsible for briefly increasing the Na+ permeability of the membrane during the rising phase of the nerve impulse? a. the sodium-potassium pump b. the voltage gated potassium channel c. the voltage gated sodium channel d. the stimulus gated sodium channel e. the ligand gated ion channel
- During the refractory period a) if a neuron reaches threshold the action potential goes to completion b) No stimulus of any strength will trigger a new action potential c) It is possible to trigger a new action potential but only with an unusually strong stimulus d) The signal grows weaker with distance e) The neuron fires at its maximum voltage if a stimulus depolarizes the neuron to thresholdIn the hippocampus, when glutatmate is released into the synaptic cleft, but the postsynaptic cell is NOT depolarized, there is only a small postsynaptic response. Why is this the case? A. Ca++ ions block the NMDA ion channel B. Mg++ ions block the NMDA ion channel C. Glutamate is an inhibitory amino acid neurotransmitter D. There are no NMDA receptors on the postsynaptic cellThe extracellular sodium [Na+]0 is reduced in the saline bath. Following another current injection in a neuron, the membrane potential changes were recorded. a) Why has the membrane potential changed following the Na+ reduction? b) Why has the current injection produced no action potentials? c) How might you experimentally rescue action potential generation?
- Suppose axon A enters a ganglion (cluster of neurons) and axon B leaves on the other side. Shortly after an experimenter stimulates A, an impulse travels down B. We want to know whether B is just an extension of axon A or whether A formed an excitatory synapse on some neuron in the ganglion, whose axon is axon B. How could an experimenter determine the answer? Try to think of more than one good method. Presume that the anatomy within the ganglion is so complex that you cannot simply observe the course of an axon through it.If you increase the amount of neurotransmitter in the synaptic cleft, how would you expect the post-synaptic potential (PSP) to change? a) The PSP would be stronger b) The PSP would change from depolarizing to hyperpolarizing c) The PSP would not changeImagine you are studying the activity of neurons in a mouse that is awake and interacting with other mice. If you knew that an excitatory post-synaptic potential (EPSP) occurred, you _______ predict whether it would increase or decrease the likelihood of a particular behavior The neurons you are studying could be releasing ___________ because it is the major excitatory neurotransmitter in the brain that generally depolarizes postsynaptic neurons. If you wanted to study what happens when neurons are unable to make this particular neurotransmitter you could use ___________, which is a method that prevents your gene of interest from being translated. Group of answer choices A) Could not; GABA; Electron microscopy B) Could; Glutamate; Anterograde tracing C) Could; GABA; Immunohistochemistry D) Could not; Glutamate; Antisense oligonucleotides