Q: For linkage analysis, a test cross is used rather than a hybrid cross. Why is this essential? Why…
A: Test cross allows to measure the frequency of gametes indirectly which is made by an individual.…
Q: In a cross AABbCc × aabbCc, what is the probability of producing the genotype AabbCC?
A: Trihybrid cross is a cross between three hereditary characters of the various alleles. Every gamete…
Q: What would you expect to be the minimum percentage of matching peaks in an automated DNA fingerprint…
A: DNA fingerprinting also named as DNA typing, DNA profiling, genetic fingerprinting, genotyping, or…
Q: What type of trait is displayed in the pedigree above? Use the methodology discussed in the lecture…
A: Answer 1 . This pedigree shows autosomal recessive inheritance. In autosomal recessive inheritance,…
Q: If a pregnant woman had a karyotype prepared for her baby before birth, would it be more useful in…
A: The complete set of chromosomes in the cells of an organism is its karyotype. The karyotype of the…
Q: Why is Gregor Mendel considered the father of genetics
A: Genetics is a branch of biology. It is the study that focuses on genes, genetic variation, and…
Q: What are polymorphs in pharmacy? Discuss the effects of polymorphism on the physico-chemical…
A: Morphology means physical form, the shape or structure of something. When more than one form exist…
Q: Where can we apply the knowledge you gained from non-mendelian inheritance in real-life setting?
A: Mendelian principles follow the three laws postulated by George Mendel. But some inheritance pattern…
Q: From the information given, is this gene imprinted maternally or paternally? Explain your answer…
A: Albright syndrome is a genetic disease that is regulated by genomic imprinting. Genomic imprinting…
Q: . In the list of four terms below, which term is the second mostinclusive?a. Genome c. Chromosomeb.…
A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…
Q: Stefan has launched a paternity suit to determine whether he is the father of an orphan residing in…
A: Stefan has launched a paternity suit to determine whether he is the father of an orphan residing in…
Q: What was the key reason that many biologists found protein better than DNA as a candidate for…
A: Genetics is a study of genes, heredity, and genetic variation in an organism. Living organisms…
Q: Suggest how such an pedigree analysis can be usefull?
A: A gene is a sequence of nucleotides in genome that codes for a functioning molecule. There is…
Q: blood typing is often used as evidence in paternity cases in the court of law. In one case, the…
A: Genes are the specific codes of these amino acids which produces a protein and alleles is the…
Q: List the three questions asked to analyze a human pedigree.
A: Pedigree analysis is a type of graphical representation to study the inheritance of genes in humans.…
Q: (b) Following figure is showing the DNA fingerprint analysis on the one locus of a man with four…
A: During cell division, deoxyribonucleic acid (DNA) is an inherited molecule that passes genetic…
Q: Consider Mendelian traits versus polygenic traits. What impact do modifications, such as those…
A: CRISPR-Cas9 has recently become a popular set of tools for genetic engineering. By targeting…
Q: What technique was originally used by geneticists to determine that the human traits you observed in…
A: The idea since long has been prevailing that the human traits are inherited in human society. After…
Q: Explain why we use both Giemsa and DAPI when studying human genetics, and not just one or the other.…
A: In Human Genetics, both dead and living cells need to be reported for statistical purposes.
Q: Does thephenotype of an organism automatically change when achange in genotype occurs? Why or why…
A: In biology, any measurable attribute or trait, whether acquired or inherited, of an organism. An…
Q: Why should the term DNA relative replace the more popular term blood relative when referring to…
A: DNA Relatives: Identifying relatives over any branch of the family tree is recognized…
Q: B
A: Genetic condition in which an individual receives two copies of genes, one copy from each parent…
Q: What is pedigree analysis? Suggest how such an analysis, can be useful.
A: A gene is a sequence of nucleotides in genome that codes for a functioning molecule. There is…
Q: What kind of molecular event was likely to have generated thus polymorphism?
A: DNA is deoxyribonucleic acid which is the genetic material responsible for transferring genetic…
Q: illustrate several applications of the chi-square test pertinent to genetics.
A: A chi-square test (X2) is a statistical procedure which is used in decision making in case of…
Q: How do you find a pedigree LOD score?
A: Pedigree analysis is the way in which a single inherited trait in a group of related individual is…
Q: As a genetic counselor, you inform Susan and John that a blood test for cystic fibrosis is…
A: A genetic counselor assesses the risk of having various inherited conditions. For example, the…
Q: AA AD AA AA AA AA AA AC s) Use the pedigree provided above to answer the following questions: a.…
A: Several basic modes of inheritance exist for single-gene disorders: autosomal dominant, autosomal…
Q: While traits Mendel worked with all adhered to his principles of inheritance, this is not the norm…
A: Mendel proposed three laws of inheritance: the law of dominance, the law of independent assortment,…
Q: What are the usefullness of pedigree analysis?
A: Pedigree charts are the diagrams that illustrates the phenotypes or genotypes for the particular…
Q: Which of the experiments Mendel performed led him to distinguish alleles as dominant or recessive?
A: Mendel analysed seven characteristics of pea plants, including plant height, pod form and colour,…
Q: What type of pedigree chart would you use to trace the inheritance of hitchhiker's thumb in your…
A: Hitchhiker’s thumb refers to the hypermobile thumb. This is an unusual type of thumb which can be…
Q: What techniques are employed in determination of Race/Ancestry?
A: There are two methods used by the forensic anthropologists to determine ancestry- visual…
Q: II 1 2 3 4 II 2. Write the genotype of the following individuals below based on the pedigree above.…
A: According to our guideline we can answer only the first question. So, upload other questions…
Q: If identical twins share 100% of the same genes, why do they have different fingerprints?
A: There are two kinds of twins namely the monozygotic twins and the dizygotic twins. Identical twins…
Q: genetics looking at a pedigree, describe how a patteren ELIMINATES the possibility of a particular…
A: Patterns of inheritance in humans include autosomal dominance and recessiveness, X-linked dominance…
Q: does a positive or negative interference reduce the distance between two loci
A: Genetic interference is, a phenomenon where the occurrence of one crossover inhibits or increases…
Q: Francis Galton, a geneticist of the pre-Mendelian era, devised the principle that half of our…
A: The study of genes and their functions is known as genetics. Genetics enables a person to comprehend…
Q: Would the mutant strain have an advantage over the wild- type strain? Explain your answer
A: A mutation is a permanent change in the DNA of a cell such that the sequence deviates from what is…
Q: As a genetic counselor, you inform Susan and John that a blood test for cystic fibrosis is…
A: Genetic counselor
Q: What are the symbols used in the human pedigree analysis?
A: Pedigree images show the genotypes or phenotypes of a particular organism and its ancestors. These…
Q: So why the barr bodies cannot be seen in the experiment?
A: Each organism's DNA sequence is unique. Its base-pair sequence might vary from time to time. It is…
Q: Consider the following pedigree below for a rare autosomal trait. Be sure to take into account the…
A: the probability that individual B is heterozygous:
Q: Why can a protein be used as evidence for common ancestry?
A: Complete life on earth emerged from a solitary common ancestor, & our genes mirror this common…
Q: had a karyotype prepared for her baby before birth, would it be more useful in predicting the risk…
A: Down`s syndrome, also known as trisomy 21 is a genetic disorder caused when abnormal cell division…
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- If there is no genetic variation within a population for a given trait, what is the heritability for the trait in the population?A botanist studying water lilies in an isolated pond observedthree leaf shapes in the population: round, arrowhead, and scalloped.Marker analysis of DNA from 125 individuals showed theround-leaf plants to be homozygous for allele r1, while the plantswith arrowhead leaves were homozygous for a different allele atthe same locus, r2. Plants with scalloped leaves showed DNA profileswith both the r1 and r2 alleles. Frequency of the r1 allele wasestimated at 0.81. If the botanist counted 20 plants with scallopedleaves in the pond, what is the inbreeding coefficient F forthis population?At the molecular level, explain why quantitative traits often exhibita continuum of phenotypes within a population. How does theenvironment help produce this continuum?
- Marcia saw an ad on television for ancestry DNA testingand thought, ”Why not?” She ordered a kit, swabbedher inner cheek, and returned the kit for analysis. Severalweeks later, she was surprised to learn that she was 17 percentNative American. An elderly great aunt confirmed that her mother’s family intermarried with members of Native American tribes in the Pacific Northwest in the early twentieth century. To investigate her maternal heritage, Marcia ordered a mitochondrial DNA (mtDNA) test, which confirmed her Native American ancestry. Based on these genetic results, she applied to several Native American tribes for enrollment as a tribal member. She was shocked when she was turned down. In discussions, tribal officials told her that DNA alone is not sufficient to define who is Native American. Tribal standards for enrollment vary, but usually cultural attributes such as knowledge of the language, customs, and history of the tribe are important considerations for enrollment decisions.…In a particular population of mice, certain individualsdisplay a phenotype called short tail, which is inherited as a dominant trait. Some individuals display arecessive trait called dilute, which affects coat color.Which of these traits would be easier to eliminatefrom the population by selective breeding? Why?Many people are surprised to learn that,while each individual’s fingerprints are unique, the totalnumber of fingerprint ridges is highly heritable, about 90%heritability in many populations. What does high heritabilityof this trait mean?
- What value do you place on ancestry DNA tests? What type of impression are the Ancestry DNA commercials giving about the relationship between biology, race, ethnicity & culture?You conduct an RFLP analysis of head weight in one strain of cabbage;you determine that seven QTLs affect this trait. In anotherstrain of cabbage, you find that only four QTLs affect this trait.Note that both strains of cabbage are from the same species, althoughthey may have been subjected to different degrees of inbreeding.Explain how one strain can have seven QTLs andanother strain four QTLs for exactly the same trait. Is the secondstrain missing three genes?In March 2013, the American Journal of HumanGenetics published a report that an AfricanAmerican man who submitted his genome forcommercial genealogical analysis had a Y chromosome whose sequence was very different from thatof other Y chromosomes that had been characterized previously. The investigators then found thatcertain males among the Mbo (an ethnic group inCameroon) shared many of the polymorphisms firstfound in this African-American man. How do youthink these findings would have altered estimates ofwhen a man carrying the MRCA for the human Ychromosome would have lived on the earth?
- Let’s suppose that weight in a species of mammal is polygenic, andeach gene exists as a heavy and light allele. If the allele frequenciesin the population are equal for both types of alleles (i.e., 50%heavy alleles and 50% light alleles), what percentage of individualswill be homozygous for the light alleles in all of the genesaffecting this trait, if the trait was determined by the followingnumber of genes?A. TwoB. ThreeC. FourThe equation p2+ 2pq + q2= 1 representing theHardy-Weinberg proportions examines genes withonly two alleles in a population.a. Derive a similar equation describing the equilibrium proportions of genotypes for a gene withthree alleles. [Hint: Remember that the HardyWeinberg equation can be written as the binomialexpansion (p + q)2.]b. A single gene with three alleles (IA, IB, and i) isresponsible for the ABO blood groups. Individualswith blood type A can be either IA IAor IA i;those with blood type B can be either IB IBor IB i;people with AB blood are IA IB, and type O individuals are ii. Among Armenians, the frequency of IAis0.360, the frequency of IBis 0.104, and the frequencyof i is 0.536. Calculate the frequencies of individuals in this population with the four possible bloodtypes, assuming Hardy-Weinberg equilibrium.In Problems 15–17, you will see that because matingbetween individuals within populations at Hardy-Weinbergequilibrium is random, it is possible to predict…On the assumption that the two profiles arise from twogenetically related individuals, law enforcement agenciespursue relatives of the person whose profile is stored in theDNA database. Testing in these cases is known as familialDNA testing. Should such searches be considered scientificallyvalid or even ethical?