Answer the following questions based on the graph below. pH-log solubility 2 4 6 pH 10 12 14 15. Why type of a drug classification can be assumed for a drug that demonstrates this type of a pH- solubility profile? log solubility

Fundamentals Of Analytical Chemistry
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ISBN:9781285640686
Author:Skoog
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Chapter21: Potentiometry
Section: Chapter Questions
Problem 21.22QAP
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Answer the following questions based on the graph below.
pH-log solubility
1
2
4
10
6
8
pH
12
14
15. Why type of a drug classification can be assumed for a drug that demonstrates this type of a pH-
solubility profile?
a. WA
b. WB
c. NE
16. What is the approximate pka of this drug?
а. 2
b. 6
C.
10
d. 12
17. What is the log S, for this drug?
а. О.7
b. 1.4
c. 3.2
d. 4.3
log solubility
Transcribed Image Text:Answer the following questions based on the graph below. pH-log solubility 1 2 4 10 6 8 pH 12 14 15. Why type of a drug classification can be assumed for a drug that demonstrates this type of a pH- solubility profile? a. WA b. WB c. NE 16. What is the approximate pka of this drug? а. 2 b. 6 C. 10 d. 12 17. What is the log S, for this drug? а. О.7 b. 1.4 c. 3.2 d. 4.3 log solubility
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