As a genetic engineer, you have been given the following task:alter a protein’s structure by converting a specific amino acidsequence that forms an extended a-helix to one that formsa b-barrel. What types of amino acid are probably in thea-helix, and which ones would you need to substitute?

Organic And Biological Chemistry
7th Edition
ISBN:9781305081079
Author:STOKER, H. Stephen (howard Stephen)
Publisher:STOKER, H. Stephen (howard Stephen)
Chapter9: Proteins
Section: Chapter Questions
Problem 9.58EP
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As a genetic engineer, you have been given the following task:
alter a protein’s structure by converting a specific amino acid
sequence that forms an extended a-helix to one that forms
a b-barrel. What types of amino acid are probably in the
a-helix, and which ones would you need to substitute?

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