As stated in the text, bacteriophages have been discovered with the following base substitutions in their DNA: (a) dUMP completely substituting for 'TMP (b) 5-hydroxymethyl-dUMP completely substituting for d'TMP (c) 5-methyl-dCMP completely substituting for dCMP For any one of these cases, formulate a set of virus-coded enzyme activities that could lead to the observed substitution. Write a balanced equation for each reaction you propose.

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter19: Genomes And Proteomes
Section: Chapter Questions
Problem 1ITD: Below is a sequence of 540 bases from a genome. What information would you use to find the...
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As stated in the text, bacteriophages have been discovered with the following
base substitutions in their DNA:
(a) dUMP completely substituting for 'TMP
(b) 5-hydroxymethyl-dUMP completely substituting for d'TMP
(c) 5-methyl-dCMP completely substituting for dCMP
For any one of these cases, formulate a set of virus-coded enzyme activities
that could lead to the observed substitution. Write a balanced equation for
each reaction you propose.
Transcribed Image Text:As stated in the text, bacteriophages have been discovered with the following base substitutions in their DNA: (a) dUMP completely substituting for 'TMP (b) 5-hydroxymethyl-dUMP completely substituting for d'TMP (c) 5-methyl-dCMP completely substituting for dCMP For any one of these cases, formulate a set of virus-coded enzyme activities that could lead to the observed substitution. Write a balanced equation for each reaction you propose.
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