Assume that a recessive autosomal disorder occurs in 1 of 10,000 individuals (0.0001) in the general population and that in this population about 2 percent (0.02) of the individuals are carriers for the disorder. Estimate the probability of this disorder occurring in the offspring of a marriage between first cousins. Compare this probability to the population at large.

Assume that a recessive autosomal disorder occurs in 1 of 10,000 individuals (0.0001) in the general population and that in this population about 2 percent (0.02) of the individuals are carriers for the disorder. Estimate the probability of this disorder occurring in the offspring of a marriage between first cousins. Compare this probability to the population at large.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter5: The Inheritance Of Complex Traits

Section: Chapter Questions

Problem 13QP: If there is no genetic variation within a population for a given trait, what is the heritability for...

See similar textbooks

Similar questions

If 98 out of 200 individuals in a population express the recessive phenotype, what percent of the population are heterozygotes?
If the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by only one known clinically relevant allele is 1/8500 in a given population, what is the frequency of the wild type allele? Please give your answer as a percentage to 3 decimal places, do not include the % symbol.
Consider rare disorders in a population caused by an autosomal recessive mutation. From the frequencies of the disorder in the population given, calculate the percentage of heterozygous carriers: 0.09
In Sweden 1/500 are born with an autosomal recessive disorder called thalassemia. What is the carrier frequency within the population?
If the frequency of a homozygous recessive disorder is 1 in 10,000, the frequency of the dominant allele is ________ % and the heterozygous genotype frequency is ________ %.
Suppose that two parents are both heterozygous for sickle cell anemia, which is an autosomal recessive disease. They have seven children. Use the binomial theorem to determine the probability that three of the children have sickle cell anemia and four children are healthy. Round your answer to the nearest hundredth
If 98 out of 200 individuals in a population express the recessive phenotype, what percent of the population are heterozygotes? Show a clear solution.
Tay–Sachs disease is an autosomal recessive disorder. AmongAshkenazi Jews, the frequency of Tay–Sachs disease is 1 in 3600. If theAshkenazi population is mating randomly with respect to the Tay–Sachsgene, what proportion of the population consists of heterozygouscarriers of the Tay–Sachs allele?
If a trait determined by an autosomal recessive allele occurs at a frequency of 0.25 in a population, what are the the allelic frequencies? Assume Hardy-Weinberg equilibrium and use A and a to symbolize the dominant and recessive alleles, respectively.
Cystic fibrosis is a genetic disease mostly affecting people of European descent that is caused by a recessive allele. You sample 1000 people for this allele and find 772 homozygous normal individuals, 221 heterozygotes, and 7 people homozygous for cystic fibrosis. Is this population in Hardy-Weinberg equilibrium?
If a particular population of diploid individuals is in equilibrium and contains 16% homozygous dominant individuals, 48% heterozygotes, and 36% homozygous recessive individuals, what is the frequency of the recessive allele in this population?
If the frequency of those homozygous for a rare clinically relevant allele that causes an autosomal monogenic recessive condition in a given population of 15 million individuals is 1/8500, how many individuals are likely to be carriers of the causative mutation? Please give your answer as a whole number.