Consider rare disorders in a population caused by an autosomal recessive mutation. From the frequencies of the disorder in the population given, calculate the percentage of heterozygous carriers: (a) 0.0064 (b) 0.000081 (c) 0.09 (d) 0.01 (e) 0.10
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Consider rare disorders in a population caused by an autosomal
recessive mutation. From the frequencies of the disorder in
the population given, calculate the percentage of heterozygous
carriers:
(a) 0.0064
(b) 0.000081
(c) 0.09
(d) 0.01
(e) 0.10
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- The inability to fold your tongue is an autosomal recessive trait. Assuming that the population being studied is in Hardy-Weinberg equilibrium with respect to this particular gene, what percentage of the population would be expected to be heterozygous carriers if 9% of the population is known to be homozygous recessive?An hypothesis for the extinction of the dinosaurs is that the earth had been hit by a gigantic meteor that caused the death of those big reptiles. In that case the entire genetic pool of those animals has been destroyed, invalidating the Hardy-Weinberg equilibrium. In Genetics what is this type of gene frequency change called?If the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by a rare clinically relevant allele is 1/8500 in a given population, what is the carrier frequency? Please give your answer as a percentage to 3 decimal places, do not include the % symbol. ANSWER: In a population where the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by only one known mutation is 1/8500 the carrier frequency is a percent.
- Albinism is due to a recessive allele of an autosomal gene. Let a represent the albino allele and A represent the normal non-albino allele. If one out of every 10,000 people were albino and assuming that the population is in Hardy-Weinberg equilibrium, A. what would be the phenotype frequencies of albino and non-albino ? B. what would be the allele frequencies of a and of A? C. what fraction of people can be expected to be of the genotype Aa? D. what fraction of people can be expected to be of the genotype AA?The recessive allele that causes Ellis– van Creveld syndrome when homozygous has a frequency of about 0.07 in the Amish population of Pennsylvania, although its frequency is only about 0.001 in the generalpopulation. How many persons out of one thousand in the Amish population would be expected to have the disease? How many out of one million in the general population?what is the meaning of fitness ?what two things do you suppose govern the rate of evolution by natural selection?
- Which of the following conclusions are MOST likely to be supported by genetic evidence? A. Some modern-day organisms did not exist in the past. B. Some organisms found in the fossil record do not currently exist. C. Environmental change affected the fitness of individuals differently based on their traits. D. Some disease-causing traits may remain in a population because their alleles provide an advantage to heterozygotes.Which evolutionary forces a. cause an increase in genetic variation both within and between populations? b. cause a decrease in genetic variation both within and between populations? c. cause an increase in genetic variation within populations but cause a decrease in genetic variation between populations?You are studying a population of penguins in Antarctica. Your DNA analysis of this population reveals that for the feather color pattern gene, 35 individuals are homozygous dominant, 35 individuals are heterozygous, and 30 individuals are homozygous recessive. After observing this population for several years, you repeat your DNA study and find that the current generation of penguins has 15 individuals that are homozygous dominant, 10 individuals that are heterozygous, and 75 individuals that are homozygous recessive. Which of the following hypotheses for this data would be supported by this data based on your understanding of Hardy-Weinberg equilibrium? This population of penguins is maintaining Hardy-Weinberg equilibrium due to its large population size. The penguins are randomly choosing mates, which has led to Hardy-Weinberg equilibrium. The penguins are very isolated, which is preventing gene flow from affecting Hardy-Weinberg equilibrium. The recessive phenotype in…
- Cystic fibrosis is a genetic disease mostly affecting people of European descent that is caused by a recessive allele. You sample 1000 people for this allele and find 772 homozygous normal individuals, 221 heterozygotes, and 7 people homozygous for cystic fibrosis. Is this population in Hardy-Weinberg equilibrium?A given autosomal locus has three possible alleles (A1, A2, and A3). Assuming that the numbers of individuals with the six possible genotypes are as follows, what would be the frequency of the A1 allele in the population? A1A1 = 30 A1A2 = 27 A2A2 = 12 A1A3 = 17 A2A3 = 10 A3A3 = 4 What would be the frequency of the A3A3 genotype? Assume the population is under Hardy-Weinberg equilibrium. A. 0.182 B. 0.27 C. 0.03 D. 0.317 E. 0.107 F. 0.09You are studying the genetics of an enzyme found in fish. In the population in one lake, the value of pis 0.13 and the value of q is 0.87. Which percentage of the population would be predicted to have heterozygous genotypes for this gene if the population is in Hardy-Weinberg equilibrium?