PaneCreate a diagram which illustrates the typical signalling mechanism of action of g protein coupledand possible routes of communication (autocrine etc.). Should show the specific moleculesinvolved, the mechanisms of signal transduction and indicate the different pathways that areactivated. It should include a specific example of a receptor, ligand and signalling pathway foreach general class. Include as wide a variety of ligands and modes of action as you can. for anovel pathway.SuperfamilyGive the superfamily to which the receptor belongsAccessionGive the Uniprot accession numberNameGive the molecule nameSpeciesGive the speciesLigandWhat is the ligand, or class of ligands which bind to this receptor?KeyWhat are the physiological processes involved? Is this autocrine,physiologicalparacrine or endocrine or some combination of them? What is thepathology of the receptor?processinvolvedWhat are the downstream actions of the receptor? Which moleculesdoes it interact with, how, and to what effect? How rapidly doe theeffects appear?Mechanism ofactionGive one key journal reference in Vancouver format that describes themode of action of the receptorKey referenceO FocuswordsEnglish (United Kingdom)MacBook Air

Answered: Image /qna-images/answer/273967ca-aa68-42cc-b192-f4b17c4cf8a8.jpg

ate a diagram which illustrates the typical signalling mechanism of action of g protein couplec and possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can. for a

ate a diagram which illustrates the typical signalling mechanism of action of g protein couplec and possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can. for a

Anatomy & Physiology

1st Edition

ISBN:9781938168130

Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Chapter17: The Endocrine System

Section: Chapter Questions

Problem 1ILQ: Visit this link (http://openstaxcollege.org/l/hormonebind) to watch an animation of the events that...

See similar textbooks

Similar questions

Outline the three general means by which binding of a water soluble extracellular chemical messenger to its matching surface membrane receptor brings about the desired intracellular response.
Give an example of contact-dependent signaling. What are some proteins involved?
Compare and contrast signaling via G-protein coupled receptor, receptor tyrosine kinases, nuclear receptor. Please name at least one ligand/receptor for each pathway. Also describe the 'fast' and 'slow' responses mediated by ligand binding
discuss the G-protein coupled receptors structure and overview of G-protein dependent signaling mechanism?
Explain how an indirect neurotransmitter receptor mechanism (like A-G linked receptor) conduct cell signaling?
E: Using either GPCRs (G-protein couples receptors) or RTKs (Receptor tyrosine kinases), describe: 1. How ligand binding activates the receptor. Ex: which proteins are involved? what changes can occur to the receptor after binding the ligand? 2. A signal transduction pathway that occurs due to the ligand binding (must include a secondary messenger). 3. Any cellular response due to the ligand binding. 4. A way that the signal pathway is regulated.
Explain how G Protein Coupled receptors activate G proteins and how RGS (Regulator of G Protein Signaling) inactivate G proteins.
Briefly explain how integrin inside-out and outside-in signaling is different structurally and functionally? (hint: explain what happened to ligand binding and conformation)
. Compare and contrast signalling through a ligand-gated ion channel and a G-protein coupled receptor, using specific examples.
The G protein coupled receptor (GPCR) pathway elicits diverse intracellular responses in different cells. The basic steps of GPCR signaling are outlined in this diagram. Which of the following statements correctly describes the process of GPCR signaling? The GPCR activation is reversible after the signal of the ligand diminishes. The membrane-embedded enzyme uses GTP as a secondary messenger to initiate gene expression. The ligand attaches to both the GPCR and the membrane-embedded enzyme to activate the GPCR pathway. The ligand-bound GPCR sends a GTP molecule to an enzyme in the membrane and switches it into an active state.
Why do we need to identify and determine the function of every single molecule involved in cell signalling? Provide one concrete example of an application of an elucidated cascade of events in cell signalling. (The answer should be no less than 300 words)
Compare and contrast GPCR and RTK signaling. What role does GTP play in each? What role does phosphorylation play? How is each signal differently amplified? How do these two signaling types compare to steroid signaling with respect to gene activation?