(b) Provide a mechanism for the coupling of Boc-Gly-OH with H-Phe- O'Bu using EDCI, DMAP and Hünig's base. Ph EDCI, DMAP Hunig's base tolygon me fox tolgyklot H3N Ph N=C=N Hunig's base= yay EDCI = DMAP =

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter24: Amines And Heterocycles
Section24.9: Heterocyclic Amines
Problem 21P
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(b) Provide a mechanism for the coupling of Boc-Gly-OH with H-Phe-
O'Bu using EDCI, DMAP and Hünig's base.
Ph
EDCI, DMAP
Hunig's base
tot gou
OH
to
p
of
H₂N
EDCI =
+
N=C=N
DMAP =
Hunig's base =
Ph
yay
Transcribed Image Text:(b) Provide a mechanism for the coupling of Boc-Gly-OH with H-Phe- O'Bu using EDCI, DMAP and Hünig's base. Ph EDCI, DMAP Hunig's base tot gou OH to p of H₂N EDCI = + N=C=N DMAP = Hunig's base = Ph yay
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