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- Penicillin uses which mechanism of antibiotic action against bacterial cells? Inhibition of cell wall synthesis Inhibition of protein synthesis Alteration of cell membranes Inhibition of nucleic acid synthesisExplain the phenomenon of drug resistance from the standpoint of microbial geneticsPrepare a poster that depicts how to multiply and divide common fractions to calculate drug dosages.
- Which of the following does NOT describe a mechanism for drug resistance? Prevention of drug entry into the cell Production of proteins that bind and sequester the drug Creation of new plasmids upon drug treatment Changes in the structure of the drug's target Inactivation of the drug by hydrolysisIn terms of drug development, rank the following microbes from most difficult (1) to least difficult (3): Group of answer choices helminths fungi bacteriaWhat is your personal comment on the relevance of this application? Refer to the study below https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824784/ Riboswitches as Drug Targets for Antibiotics Vipul Panchal* and Ruth Brenk*
- List four mechanisms that bacteria have developed through mutation to resist antimicrobial drugsChoose the combination of answers that most accurately completes the statement. Which statement is not an aim in the use of drugs in antimicrobial chemotherapy? The drug should a. have selective toxicity b. be active even in high dilutions c. be broken down and excreted rapidly d. be microbicidalUsing a schematic diagram, illustrate the process of the following stages of drug development:Method of Drug Discovery: Rational Design Process, Pre-Clinical Trials and Clinical Trials
- Technically speaking, which antimicrobial drugs are produced naturally? Biofilms Antibiotics Semisynthetics SyntheticsCan you think of a situation in which it would be better for a drug to be microbistatic rather than microbicidal? Discuss thoroughly.Discuss two possible 'magic bullets' you have already learned about for targeting bacteria with drugs.