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Briefly, describe enzyme multiplicity and broad substrate selectivity for cytochrome P450.
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- . List and describe the components of the cytochrome P450electron transport system. What is the role of eachcomponent?Using the ActiveModel for enoyl-CoA dehydratase, give an example of a case in which conserved residues in slightly different positions can change the catalytic rate of reaction.What are the measures to inhibit the Maillard reaction in undesirable situations. please explain detailed
- In what way is the observed mode of action of hexokinase consistent with the induced-fit theory of enzyme action?Briefly describe the role of nucleophilic catalysis in the mechanism of the chymotrypsin reaction.Considering PNPP → PNP reaction, would you expect to see more intense or pale color for the reaction that contain the inhibitor? Explain.
- Discuss two other enzymes that are used in therapeutic use in humans and why they do not affect human cells?Describe the experimental evidence that supports lysozyme’s catalysis by acid– base catalysis, covalent catalysis, and transition state stabilization.The effect of uncompetitive inhibitor is reversed by increasing substrate concentration?
- Explain the observation made when papase is added to the reaction catalyzed polyphenoloxidase?Briefly discuss the REDUCTIVE TCA CYCLE.PLP can catalyze both \alpha, \beta elimination reactions and \beta, \gamma - elimination reactions. Propose a mechanism for the following PLP - catalyzed \beta, \gamma elimination