Briefly explain how Genome Wide Association Studies (GWAS) are done. Then, using this example of a Manhattan Plot explain what each of the X-axis and the Y-axis signifies in a GWAS.

Q: How is the color of the spot coverted into useful data if data is collected from a Vicrochip DNA…

A: DNA microarray is a chip-based technique where a collection of microscopic DNA spots attached to a…

Q: How can the concept of recombination frequency be used in genetic mapping?

A: It is the process of determining the location of genes on a chromosome that is called genetic…

Q: List at least two ways in which computerized analysis oftranscriptomes aids genetic research.

A: Genetic research refers to the study of human deoxyribonucleic acid (DNA) to order to know the genes…

Q: Draw a figure describing the steps in MANUAL Sangers sequencing not automatic sangers sequencing.…

A: Sanger sequencing results in the formation of extension products of various lengths terminated with…

Q: Discuss theh type of information that genome-wide association studies can provide

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Using illustrations describe the structure of a typical cloning vector and discuss the functions of…

A: "Biotechnology" is the use of our knowledge of biological processes to the development of beneficial…

Q: Explain Two strategies for assembling whole genome sequences.

A: All the genetic information of an organism is known as its genome. Genome assembly is defined as the…

Q: Briefly explain the contribution that Francis Crick made to the study of genetics

A: Francis H. C. Crick was a renowned British molecular biologist, biophysicist, and neuroscientist.

Q: In the accompanying diagram, the cate the positions of restriction sites in two alterna- tive DNA…

A: RFLP (Restriction Fragment Length Polymorphism) is a technique that exploits the variation in the…

Q: You want to make a library with DNA fragments averaging over 100 kb in length. Which vectors…

A: A genomic library is a constitutive collection of the total genome of a single organism. Genomic…

Q: • Was the negative electrode or the positive electrode positioned closer to the bottom of the gel? •…

A: A microsatellite is a sequence of DNA, it does not code for protein means they are present in the…

Q: Describe step 1: hybridization of template and primer in automated sanger sequencing

A: Introduction  Sanger sequencing is also known as the “chain termination method”. It is a method for…

Q: What are three benefits Ion torrent sequencing has over sanger sequencing

A: DNA is an important biomolecule in the cell as it is the genetic material for most of the organisms…

Q: If “the human genome sequence” does not really exist, can you think of better ways in which we might…

A: Human genome sequence projects initially started in 1990. Its aim was to completely sequence all the…

Q: Compare and contrast the use of SNP genotyping:(i) in the positional cloning of Mendelian…

A: The single nucleotide polymorphism (SNP) genotyping is the technique used to measure the genetic…

Q: Compare and contrast linkage analysis and genome-wide association studies. How are they similar? How…

A: Genetics is the branch of biology that deals with the study of genes, genetic variation, and…

Q: ​Describe the components of the human genome.​ proper explanation and diagram

A: The cell nucleus is the most remarkable organelle in the eukaryotic cell and may be the main and…

Q: Describe two ways in which genome database information is used to study human disease genes.

A: The genome encodes all the information of the deoxyribonucleic acid, the macromolecule containing…

Q: Design forward and reverse primers to amplify this ENTIRE locus by PCR. Design each primer to be 10…

A: The forward and reverse primers are both important components used in PCR for amplifying a target…

Q: Briefly describe the steps or methods for studying genes.  Start with targeting a gene region and…

A: Gel electrophoresis is a strategy for investigating DNA dependent on its size (base-pair length). As…

Q: Briefly explain the contribution that Gregor Mendel made to the study of genetics

A: Gregor Johann Mendel was a German scientist. He worked on seven characteristics of pea plants: pod…

Q: With the many high throughput experiments that are used in biomedical research, how are some ways to…

A: High-throughput screening (HTS) is a method for scientific experimentation especially used in…

Q: process of overlap assembly in whole genome sequencing

A: Genome sequencing Genome sequencing or gene sequencing is a way of arranging nucleotides the n the…

Q: Explain why phenol:chloroform is used in the isolation of genomic DNA (What is the end result and…

A: Ans-  When DNA-containing samples are extracted with acidic phenol, the DNA is denaturized, and…

Q: A. Why are mammals hard to clone?  B. What were the names of the first two cloned cows?

A: According to the question, we have to mention the reason why mammals are hard to clone. In addition…

Q: Give the scope of the following fields in Applied Genetics: Instruction: No plagiarism. Answer…

A: Applied Genetics of the white field which main change the pattern of gene expression. Thereby this…

Q: Why might the genomic analysis of dogs be particularly useful for investigating the genes…

A: Genome: Genome is a total of genes in an organism. Genome size vary with organism. It can be as…

Q: Discuss how Genome-wide association studies (GWAS) can be used to identify genetic risk loci for (a)…

A: GWAS helps in screening the genome across the databases to find the desirable results without having…

Q: What genetic method or technique would you consider as the most advanced? Why? In what fields of…

A: Gene is the Smallest unit of of heredity. Genes are the part of DNA which are responsible for…

Q: In your opinion, what is the most compelling reason to upload transcriptome data to free, public…

A: Transcriptome means a series of mRNA or messenger RNA, molecules expressed in an organism. The human…

Q: Refer to the figure. What method would you use if you wanted to determine the sequence of the cDNA…

A: cDNA is complementary DNA. This DNA is artificially synthesized from the mRNA template. In genetic…

Q: The length of the entire human reference genome is about

A: Human reference genome is a blueprint of DNA which is used as a standard comparison in basic…

Q: Describe how genome-wide association studies have led to new understandings about the structure and…

A: Systems biology is a method for comprehending complex biological systems. It necessitates the…

Q: List some of the effects and practical applications of molecular genetic analyses.

A: MOLECULAR GENETIC ANALYSIS:-  Molecular genetics is the study of genetic material- its structure,…

Q: Draw a simplified schematic for Heidelberg screening to identify zygotic genes.

A: Zygotic mutants P     z/+ ♀      x      z/+♂ F1    z/z           z/+    z/+   +/+

Q: Traditional Sanger sequencing has largely been replaced in recent years by next-generation and…

A: BASIC INFORMATION  Gene Sequencing  It is a process through which the arrangement of of the…

Q: Give and explain two reasons for the importance of adding a woody plant to the list of completed…

A: Woody plants are important components of the global ecosystem; they play an important role in…

Q: Explain the rationale behind the use of the “bag of worms” phenotype as a way to identify…

A: A mutation refers to an alteration in the genome or genetic material of a living organism’s cells or…

Q: The best molecular technique to quantify the gene transcripts is (write in fu!!).

A: The Central Dogma concept states that "DNA makes RNA and RNA makes protein". This concept is…

Q: Briefly explain why RNA-seq gives more information about the transcriptome than does microarray…

A: Messenger (m-RNA) ribonucleic acid is known to be transcribed from the DNA molecule, which is the…

Q: Discuss the sequencing methods of the human genome used in 2000- the strength and limitations (This…

A: A genome is a creature's finished arrangement of deoxyribonucleic corrosive (DNA), a synthetic…

Q: What it is called when two regions of the genome in different species share similarities like those…

A: Genome Genome can be defined as the the complete set of of gene of an living organism.

Q: Discuss what is meant by the term genome

A: Organisms are classified as monoploid, diploid, triploid, tetraploid, etc based on the number of…

Genome annotation

The technique of linking biological information to genome sequences is termed genome annotation. Gene annotation is the method of identifying gene locations and coding sections. It helps us understand what these genes are doing in the body through establishing structural characteristics and linking them to the actions of various proteins.