With the many high throughput experiments that are used in biomedical research, how are some ways to integrate those datasets using systems biology? For example, if you had a microarray dataset that annotated gene expression levels and a proteomics dataset that identifed protein interactions, how could you jointly use both datasets to identify markers for a disease? Explain each step.

Concepts of Biology
1st Edition
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:Samantha Fowler, Rebecca Roush, James Wise
Chapter10: Biotechnology
Section: Chapter Questions
Problem 12CTQ: Describe two of the applications for genome mapping.
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With the many high throughput experiments that are used in biomedical research, how are some ways to integrate those datasets using systems biology? For example, if you had a microarray dataset that annotated gene expression levels and a proteomics dataset that identifed protein interactions, how could you jointly use both datasets to identify markers for a disease? Explain each step.
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