Answered: calculate the dilution required to…

calculate the dilution required to analyse the concentration of paracetamol in a commercially available paracetamol tablet. Start by dissolving the tablet in 100 mL methanol. Show working out.

Principles of Instrumental Analysis

7th Edition

ISBN:9781305577213

Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Chapter27: Gas Chromatography

Section: Chapter Questions

Problem 27.16QAP

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Acetaminophen or paracetamol, the active ingredient in many pain killers absorbs in the UV range with a λ_max at 250 nm in neutral solutions (methanol usually). Its extinction coefficient is 14 mM^-1cm^-1. Each commercially available tablet (Tylenol, Panadol or Herron) contains 500 mg paracetamol. Its molecular weight is 151.1.

Using this information, calculate the dilution required to analyse the concentration of paracetamol in a commercially available paracetamol tablet. Start by dissolving the tablet in 100 mL methanol. Show working out.

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